Introduction：Basic information about CAS 30766-12-2|Methyl 5-hydroxypyridine-2-carboxylate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Methyl 5-hydroxypyridine-2-carboxylate |
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| CAS Number | 30766-12-2 | Molecular Weight | 153.135 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 374.2±22.0 °C at 760 mmHg |
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| Molecular Formula | C7H7NO3 | Melting Point | 193.5-195.5℃ |
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| MSDS | / | Flash Point | 180.1±22.3 °C |
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Names
| Name | methyl 5-hydroxypyridine-2-carboxylate |
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| Synonym | More Synonyms |
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Methyl 5-hydroxypyridine-2-carboxylate BiologicalActivity
| Description | Methyl 5-hydroxypyridine-2-carboxylate is a phenolic acid that can found in the stems of Mahonia fortune. Methyl 5-hydroxypyridine-2-carboxylate exhibits NO inhibitory effects in vitro[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| In Vitro | Methyl 5-hydroxypyridine-2-carboxylate (compound 2) inhibits NO in LPS-stimulated RAW264.7 and BV2 cells, with IC50s of 115.67 and 118.80 μM, respectively[1]. Methyl 5-hydroxypyridine-2-carboxylate (6.25-200 μM) does not exhibit any cytotoxic effect[1]. |
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| References | [1]. Liu L, et, al. Simultaneous characterisation of multiple Mahonia fortunei bioactive compounds in rat plasma by UPLC-MS/MS for application in pharmacokinetic studies and anti-inflammatory activity in vitro. J Pharm Biomed Anal. 2020 Feb 5;179:113013. [2]. Liu L, et, al. Simultaneous characterisation of multiple Mahonia fortunei bioactive compounds in rat plasma by UPLC-MS/MS for application in pharmacokinetic studies and anti-inflammatory activity in vitro. J Pharm Biomed Anal. 2020 Feb 5;179:113013. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 374.2±22.0 °C at 760 mmHg |
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| Melting Point | 193.5-195.5℃ |
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| Molecular Formula | C7H7NO3 |
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| Molecular Weight | 153.135 |
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| Flash Point | 180.1±22.3 °C |
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| Exact Mass | 153.042587 |
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| PSA | 59.42000 |
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| LogP | 0.82 |
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| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
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| Index of Refraction | 1.552 |
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| InChIKey | YYAYXDDHGPXWTA-UHFFFAOYSA-N |
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| SMILES | COC(=O)c1ccc(O)cn1 |
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Safety Information
| Risk Phrases | 20/21/22 |
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| Safety Phrases | 24/25-36/37 |
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| HS Code | 2933399090 |
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Customs
| HS Code | 2933399090 |
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| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 5-Hydroxy-2-(methoxycarbonyl)pyridine |
| 5-Hydroxypyridine-2-carboxylic acid methyl ester |
| 5-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER |
| Methyl 5-hydroxypicolinate |
| methyl 5-hydroxypyridin-2-carboxylate |
| Methyl3-hydroxypicolinate |
| 2-Pyridinecarboxylic acid, 5-hydroxy-, methyl ester |
| Methyl 5-hydroxy-2-pyridinecarboxylate |
| 5-Hydroxy-2-pyridinecarboxylic Acid Methyl Ester |
| Methyl 5-hydroxypyridine-2-carboxylate |
| 5-Hydroxy-pyridin-2-carbonsaeure-methylester |
