Introduction：Basic information about CAS 117499-16-8|1,7-Bis-Boc-1,4,7-triazaheptane, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 1,7-Bis-Boc-1,4,7-triazaheptane |
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| CAS Number | 117499-16-8 | Molecular Weight | 303.39800 |
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| Density | 1.0±0.1g/cm3 | Boiling Point | 440.5±30.0°C at 760 mmHg |
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| Molecular Formula | C14H29N3O4 | Melting Point | / |
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| MSDS | / | Flash Point | 220.2±24.6°C |
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Names
| Name | tert-butyl N-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethylamino]ethyl]carbamate |
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| Synonym | More Synonyms |
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1,7-Bis-Boc-1,4,7-triazaheptane BiologicalActivity
| Description | 1,7-Bis-Boc-1,4,7-triazaheptane is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | Alkyl/ether |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.0±0.1g/cm3 |
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| Boiling Point | 440.5±30.0°C at 760 mmHg |
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| Molecular Formula | C14H29N3O4 |
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| Molecular Weight | 303.39800 |
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| Flash Point | 220.2±24.6°C |
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| Exact Mass | 303.21600 |
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| PSA | 88.69000 |
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| LogP | 2.79810 |
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| Index of Refraction | 1.466 |
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| InChIKey | KNORWRWRHNHJAV-UHFFFAOYSA-N |
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| SMILES | CC(C)(C)OC(=O)NCCNCCNC(=O)OC(C)(C)C |
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| Storage condition | 2-8°C |
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Safety Information
| Hazard Codes | Xi |
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| HS Code | 2924199090 |
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Customs
| HS Code | 2924199090 |
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| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| 1,7-Bis-Boc-1,4,7-triazaheptane |
| Bis(2-Methyl-2-Propanyl) (Iminodi-2,1-Ethanediyl)Biscarbamate |
| Di-tert-butyl (azanediylbis(ethane-2,1-diyl))dicarbamate |
