CAS 40632-23-3|2'-Deoxyuridine-d2-1

Introduction：Basic information about CAS 40632-23-3|2'-Deoxyuridine-d2-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 2'-Deoxyuridine-d2-1 BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	2'-Deoxyuridine-d2-1
CAS Number	40632-23-3	Molecular Weight	230.214
Density	1.5±0.1 g/cm3	Boiling Point	/
Molecular Formula	C₉H₁₀D₂N₂O₅	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	2'-deoxyuridine-5,6-d2
Synonym	More Synonyms

2'-Deoxyuridine-d2-1 BiologicalActivity

Description	2'-Deoxyuridine-d2-1 is the deuterium labeled 2'-Deoxyuridine[1]. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxudine[2].
Related Catalog	Research Areas >>Infection
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Reidy JA, et al. Deoxyuridine increases folate-sensitive fragile site expression in human lymphocytes. Am J Med Genet. 1987 Jan;26(1):1-5.

Chemical & Physical Properties

Density	1.5±0.1 g/cm3
Molecular Formula	C₉H₁₀D₂N₂O₅
Molecular Weight	230.214
Exact Mass	230.087173
PSA	104.55000
LogP	-1.70
Index of Refraction	1.603
InChIKey	MXHRCPNRJAMMIM-AQAQJVFASA-N
SMILES	O=c1ccn(C2CC(O)C(CO)O2)c(=O)[nH]1

Synonyms

2,4(1H,3H)-Pyrimidinedione-5,6-d, 1-(2-deoxy-β-L-erythro-pentofuranosyl)-

1-(2-Deoxy-β-L-erythro-pentofuranosyl)-2,4(1H,3H)-(5,6-H)pyrimidinedione

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