CAS 191729-45-0|Tenacissoside H

Introduction：Basic information about CAS 191729-45-0|Tenacissoside H, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameTenacissoside H
CAS Number191729-45-0Molecular Weight794.965
Density1.3±0.1 g/cm3Boiling Point815.4±65.0 °C at 760 mmHg
Molecular FormulaC42H66O14Melting Point/
MSDS/Flash Point235.5±27.8 °C

Names

Name12-acetoxy-1-acetyl-8-((5-((3,5-dihydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-10a,12a-dimethyltetradecahydro-1H-cyclopenta[1,2]phenanthro[1,10a-b]oxiren-11-yl 2-methylbutanoate
SynonymMore Synonyms

Tenacissoside H BiologicalActivity

DescriptionTenacissoside H is a Chinese medicine monomer extracted, isolated from Caulis Marsdeniae Tenacissimae.IC50 value:Target:In vitro: TDH significantly inhibited cells proliferation in a time-and-dose-dependent manner. TDH arrested the cell cycle in S phase and significantly inhibited PI3K and NF-κB mRNA expression, compared with blank controlled group (P < 0.05). [1]In vivo: TDH strongly inhibits tumor growth and volume. PCNA expression was significantly decreased after treatment of TDH. TDH downregulated proteins expression in PI3K/Akt-NF-κB transduction cascade (P < 0.05). [1]
Related CatalogSignaling Pathways >>Others >>OthersNatural Products >>SteroidsResearch Areas >>Cancer
References

[1]. Jia YS, et al. Antitumor Activity of Tenacissoside H on Esophageal Cancer through Arresting Cell Cycle and Regulating PI3K/Akt-NF-κB Transduction Cascade. Evid Based Complement Alternat Med. 2015;2015:464937.

Chemical & Physical Properties

Density1.3±0.1 g/cm3
Boiling Point815.4±65.0 °C at 760 mmHg
Molecular FormulaC42H66O14
Molecular Weight794.965
Flash Point235.5±27.8 °C
Exact Mass794.445251
PSA178.04000
LogP4.73
Vapour Pressure0.0±0.6 mmHg at 25°C
Index of Refraction1.551
InChIKeyHRSFCYYMBMDMOU-ZIAOJATMSA-N
SMILESCCC(C)C(=O)OC1C2C3(C)CCC(OC4CC(OC)C(OC5OC(C)C(O)C(OC)C5O)C(C)O4)CC3CCC23OC32CCC(C(C)=O)C2(C)C1OC(C)=O

Safety Information

Safety Phrases24/25
HS Code29389090

Synonyms

(3β,5α,11α,12β,14β,17α)-12-Acetoxy-3-{[2,6-dideoxy-4-O-(6-deoxy-3-O-methyl-β-D-allopyranosyl)-3-O-methyl-β-D-arabino-hexopyranosyl]oxy}-20-oxo-8,14-epoxypregnan-11-yl 2-meth ylbutanoate
Butanoic acid, 2-methyl-, (3β,5α,11α,12β,14β,17α)-12-(acetyloxy)-3-[[2,6-dideoxy-4-O-(6-deoxy-3-O-methyl-β-D-allopyranosyl)-3-O-methyl-β-D-arabino-hexopyranosyl]oxy]-8,14-ep oxy-20-oxopregnan-11-yl ester
Tenacissoside H
CAS 509-24-0|Napellonine
CAS 1310-03-8|Lead(II) hexafluorosilicate dihydrate.
Recommended......
CAS 19693-54-0|1,6-Naphthyridi CAS 19406-51-0|4-amino-2,6-din CAS 19221-04-6|2-DIMETHYLAMINO CAS 193274-82-7|tert-butyl 3-b CAS 198973-94-3|1,2-DIBENZYLPI CAS 199526-97-1|4,6-Difluoroin CAS 19945-22-3|N,N-bis(2-chlor CAS 1904-95-6|Sulfanilamide, N CAS 1929-89-1|2-Furancarboxami CAS 19156-52-6|4,5-dimethylthi CAS 19156-54-8|4,5,6,7-TETRAHY CAS 19013-12-8|4-Methyl-3-nitr CAS 19914-38-6|Boc-D-Me-Ala-OH CAS 197585-42-5|METHYL 2-METHO CAS 199926-33-5|2-ACRYLAMIDO-2 CAS 19337-60-1|3-Iodobenzene-1 CAS 196618-13-0|Oseltamivir CAS 1977-10-2|Loxapine CAS 195000-66-9|2-oxotetrahydr CAS 19714-73-9|BENZENE, 1-CYCL
Disclaimer

This site is a non-commercial website, not accept any sponsorship and advertising. The content is collated from the Internet, does not represent the position of this site, for personal reference only, please distinguish by yourself! The belongs to the original author.

Copyright © 2025 All Rights Reserved.

TOP