CAS 1206101-20-3|GLPG0634
Introduction：Basic information about CAS 1206101-20-3|GLPG0634, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | GLPG0634 | ||
|---|---|---|---|
| CAS Number | 1206101-20-3 | Molecular Weight | 410.428 |
| Density | 1.4±0.1 g/cm3 | Boiling Point | / |
| Molecular Formula | C23H18N6O2 | Melting Point | / |
| MSDS | / | Flash Point | / |
Names
| Name | N-(5-{4-[(6-Cyano-3-pyridinyl)methoxy]phenyl}[1,2,4]triazolo[1,5- a]pyridin-2-yl)cyclopropanecarboxamide |
|---|---|
| Synonym | More Synonyms |
GLPG0634 BiologicalActivity
| Description | GLPG0634 (analog) (compound176)is a pan JAK inhibitor with IC50s of 50-200 nM for JAK1/JAK2/JAK3; more information can be found in the reference patents. |
|---|---|
| Related Catalog | Research Areas >>Cancer |
| Target | JAK3:<100 nM (IC50) Tyk2:<100 nM (IC50) |
| References | [1]. http://www.google.com/patents/WO2013173506A2cl=en [2]. http://www.google.it/patents/WO2010149769A1cl=en [3]. http://www.google.com/patents/WO2010010190A1cl=en |
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C23H18N6O2 |
| Molecular Weight | 410.428 |
| Exact Mass | 410.149109 |
| PSA | 108.43000 |
| LogP | 2.26 |
| Index of Refraction | 1.733 |
| Storage condition | -20℃ |
Safety Information
| Hazard Codes | Xi |
|---|
Synonyms
| N-(5-{4-[(6-Cyano-3-pyridinyl)methoxy]phenyl}[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide |
| Cyclopropanecarboxamide, N-[5-[4-[(6-cyano-3-pyridinyl)methoxy]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]- |
| GLPG0634 |
| GLPG0634 analogue |
| GLPG0634 analog |
