Introduction：Basic information about CAS 70342-29-9|Methyl Kakuol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Methyl Kakuol |
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| CAS Number | 70342-29-9 | Molecular Weight | 208.21100 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C11H12O4 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 1-(6-methoxy-1,3-benzodioxol-5-yl)propan-1-one |
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| Synonym | More Synonyms |
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Methyl Kakuol BiologicalActivity
| Description | Methyl kakuol shows agonistic activity against TRPA1 with an EC50 of 0.27 µM[1]. |
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| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>TRP ChannelResearch Areas >>Neurological Disease |
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| Target | TRPA1 |
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| In Vivo | The maximum concentration (Cmax) of Methyl kakuol at a dose of 2 g/kg (containing 1156 µg/kg, 294 µg/kg, 452 µg/kg, 852 µg/kg asarinin, sesamin, methyl kakuol, and amide A, respectively) is 98.2 ng/mL[1]. |
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| References | [1]. Takashi Matsumoto, et al. In Vivo Pharmacokinetic Analysis Utilizing Non-Targeted and Targeted Mass Spectrometry and In Vitro Assay against Transient Receptor Potential Channels of Maobushisaishinto and Its Constituent Asiasari Radix. Molecules. 2020 Sep 18;25(18):4283. |
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Chemical & Physical Properties
| Molecular Formula | C11H12O4 |
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| Molecular Weight | 208.21100 |
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| Exact Mass | 208.07400 |
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| PSA | 44.76000 |
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| LogP | 2.01660 |
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| InChIKey | XPHIRVUYIBXETG-UHFFFAOYSA-N |
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| SMILES | CCC(=O)c1cc2c(cc1OC)OCO2 |
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| Storage condition | 2-8°C |
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Synonyms
| 1-Propanone,1-(6-methoxy-1,3-benzodioxol-5-yl) |
| Methyl kakuol |
