CAS 51219-90-0|Hexamethylphosphoramide-d18

Introduction：Basic information about CAS 51219-90-0|Hexamethylphosphoramide-d18, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Hexamethylphosphoramide-d18 BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Hexamethylphosphoramide-d18
CAS Number	51219-90-0	Molecular Weight	179.20000
Density	1.032g/cm3	Boiling Point	233ºC at 760mmHg
Molecular Formula	C₆H₁₈N₃OP	Melting Point	/
MSDS	/	Flash Point	94.7ºC

Names

Name	N-bis[bis(trideuteriomethyl)amino]phosphoryl-1,1,1-trideuterio-N-(trideuteriomethyl)methanamine
Synonym	More Synonyms

Hexamethylphosphoramide-d18 BiologicalActivity

Description	Hexamethylphosphoramide-d18 is the deuterium labeled Hexamethylphosphoramide[1].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Chemical & Physical Properties

Density	1.032g/cm3
Boiling Point	233ºC at 760mmHg
Molecular Formula	C₆H₁₈N₃OP
Molecular Weight	179.20000
Flash Point	94.7ºC
Exact Mass	179.11900
PSA	36.60000
LogP	0.77930
Index of Refraction	1.464
InChIKey	GNOIPBMMFNIUFM-NBDUPMGQSA-N
SMILES	CN(C)P(=O)(N(C)C)N(C)C
Storage condition	-20C

Safety Information

Hazard Codes	Xi
Risk Phrases	R45;R46
Safety Phrases	S45-S53

Synonyms

Octadecadeuterio-hexamethyl-phosphoramide

EINECS 257-063-4

Hexamethylphosphortriamide-D18

DE650

hexakis-trideuteriomethyl-phosphamide

Recommended......