Introduction：Basic information about CAS 142937-50-6|Triptoquinone B, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Triptoquinone B |
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| CAS Number | 142937-50-6 | Molecular Weight | 330.418 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 475.4±45.0 °C at 760 mmHg |
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| Molecular Formula | C20H26O4 | Melting Point | / |
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| MSDS | / | Flash Point | 255.4±25.2 °C |
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Names
| Name | Triptoquinone B |
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| Synonym | More Synonyms |
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Triptoquinone B BiologicalActivity
| Description | Triptoquinone B ((+)-Triptoquinone B), a sesquiterpene alkaloid, is an interleukin-1 inhibitor. Triptoquinone B shows potent inhibitory activities against interleukin 1α and β releases for human peripheral mononuclear cells[1][2]. |
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| Related Catalog | Signaling Pathways >>Immunology/Inflammation >>Interleukin RelatedResearch Areas >>Inflammation/Immunology |
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| Target | IL-1 |
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| References | [1]. Takaishi Y, et, al. Triptoquinone A and B novel interleukin-1 inhibitors from Tripterygium wilfordii var Regeli. Tetrahedron Letters. 1992 Nov; 33(47): 7177-7180. [2]. Wang XD, et, al. Terpene alkaloids from Tripterygium wilfordii. J Asian Nat Prod Res. 2005 Oct;7(5):755-9. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 475.4±45.0 °C at 760 mmHg |
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| Molecular Formula | C20H26O4 |
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| Molecular Weight | 330.418 |
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| Flash Point | 255.4±25.2 °C |
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| Exact Mass | 330.183105 |
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| PSA | 71.44000 |
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| LogP | 2.77 |
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| Vapour Pressure | 0.0±2.7 mmHg at 25°C |
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| Index of Refraction | 1.558 |
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| InChIKey | RYYRZMIBKOKIRO-UIAACRFSSA-N |
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| SMILES | CC(C)C1=CC(=O)C2=C(CCC3C(C)(CO)C(=O)CCC23C)C1=O |
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Safety Information
Synonyms
| 1,4,7(4bH)-Phenanthrenetrione, 5,6,8,8a,9,10-hexahydro-8-(hydroxymethyl)-4b,8-dimethyl-2-(1-methylethyl)-, (4bS,8S,8aR)- |
| 19-Hydroxyabieta-8,12-diene-3,11,14-trione |
| Triptoquinone B |
