CAS 91296-86-5|Difluoxacin hydrochloride
| Common Name | Difluoxacin hydrochloride | ||
|---|---|---|---|
| CAS Number | 91296-86-5 | Molecular Weight | 435.852 |
| Density | 1.409 g/cm3 | Boiling Point | 595.5ºC at 760 mmHg |
| Molecular Formula | C21H20ClF2N3O3 | Melting Point | >245ºC (dec.) |
| MSDS | ChineseUSA | Flash Point | 313.9ºC |
Names
| Name | Difloxacin Hydrochloride Salt |
|---|---|
| Synonym | More Synonyms |
Difluoxacin hydrochloride BiologicalActivity
| Description | Difloxacin hydrochloride is a broad-spectrum antibacterial drug. Difloxacin hydrochloride inhibits bacterial DNA gyrase and exhibits a concentration-dependant bactericidal effect by interference with the activity of DNA gyrase and topoisomerase IV[1]. |
|---|---|
| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
| References | [1]. Abo El-Ela FI, et al. Pharmacokinetics of difloxacin in healthy and E. coli-infected broiler chickens. Br Poult Sci. 2014;55(6):830-6. |
Chemical & Physical Properties
| Density | 1.409 g/cm3 |
|---|---|
| Boiling Point | 595.5ºC at 760 mmHg |
| Melting Point | >245ºC (dec.) |
| Molecular Formula | C21H20ClF2N3O3 |
| Molecular Weight | 435.852 |
| Flash Point | 313.9ºC |
| Exact Mass | 435.116119 |
| PSA | 65.78000 |
| LogP | 3.52380 |
| Index of Refraction | 1.629 |
| InChIKey | JFMGBGLSDVIOHL-UHFFFAOYSA-N |
| SMILES | CN1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3-c2ccc(F)cc2)CC1.Cl |
| Storage condition | 0-6°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | T+ |
| RIDADR | NONH for all modes of transport |
| RTECS | VB2008975 |
Articles34
More Articles| Determination of fluoroquinolones in chicken feces - a new liquid-liquid extraction method combined with LC-MS/MS. Environ. Toxicol. Pharmacol. 38(3) , 792-9, (2014) The application of antibiotics including fluoroquinolones to farming animals is widespread and may lead to the development of antibiotic resistance and other environmental effects. To calculate enviro... | |
| Occurrence and distribution of antibiotics in urban soil in Beijing and Shanghai, China. Environ. Sci. Pollut. Res. Int. 22 , 11360-71, (2015) The recycling of reclaimed wastewater for irrigation and road cleaning is an important strategy to minimize water scarcity in megacities. However, little is known regarding the potential accumulation ... | |
| Facile synthesis of polyaniline-coated SiO₂ nanofiber and its application in enrichment of fluoroquinolones from honey samples. Talanta 140 , 29-35, (2015) In this study, polyaniline coated SiO2 nanofibers (PANI/SiO2) was prepared by combining electrospinning technique with in-situ polymerization. The proposed strategy for the preparation of PANI/SiO2 ca... |
Synonyms
| MFCD03840489 |
| 6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid,hydrochloride |
