Introduction：Basic information about CAS 573-20-6|Vitamin K4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Vitamin K4 |
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| CAS Number | 573-20-6 | Molecular Weight | 258.269 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 388.9±30.0 °C at 760 mmHg |
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| Molecular Formula | C15H14O4 | Melting Point | 113 °C |
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| MSDS | ChineseUSA | Flash Point | 195.1±23.0 °C |
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| Symbol |
GHS05 | Signal Word | Danger |
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Names
| Name | Menadiol Diacetate |
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| Synonym | More Synonyms |
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Vitamin K4 BiologicalActivity
| Description | Vitamin K4 is a chemically synthesized Vitamin K which plays an important role in the normal blood coagulation system. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>CancerResearch Areas >>Cardiovascular Disease |
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| References | [1]. Jiang Y, et al. Vitamin K4 induces tumor cytotoxicity in human prostate carcinoma PC-3 cells via the mitochondria-related apoptotic pathway. Pharmazie. 2013 Jun;68(6):442-8. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 388.9±30.0 °C at 760 mmHg |
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| Melting Point | 113 °C |
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| Molecular Formula | C15H14O4 |
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| Molecular Weight | 258.269 |
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| Flash Point | 195.1±23.0 °C |
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| Exact Mass | 258.089203 |
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| PSA | 52.60000 |
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| LogP | 2.67 |
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| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
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| Index of Refraction | 1.580 |
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| InChIKey | RYWSYCQQUDFMAU-UHFFFAOYSA-N |
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| SMILES | CC(=O)Oc1cc(C)c(OC(C)=O)c2ccccc12 |
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| Storage condition | 2~8 ℃ |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- QJ5250000
- CHEMICAL NAME :
- 1,4-Naphthalenediol, 2-methyl-, diacetate
- CAS REGISTRY NUMBER :
- 573-20-6
- BEILSTEIN REFERENCE NO. :
- 1991457
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C15-H14-O4
- MOLECULAR WEIGHT :
- 258.29
- WISWESSER LINE NOTATION :
- L66J BOV1 C1 EOV1
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 75,111,1942
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Safety Information
| Symbol |
GHS05 |
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| Signal Word | Danger |
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| Hazard Statements | H318 |
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| Precautionary Statements | P280-P305 + P351 + P338 + P310 |
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| Hazard Codes | Xi |
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| RIDADR | NONH for all modes of transport |
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| RTECS | QJ5250000 |
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Articles2
More Articles
| Vitamin K4 induces tumor cytotoxicity in human prostate carcinoma PC-3 cells via the mitochondria-related apoptotic pathway. Jiang Y, et.al. Pharmazie 68 , 442-448, (2013)
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| One-Pot Hydroacetylation of Menadione (Vitamin K3) to Menadiol Diacetate (Vitamin K4) by Heterogeneous Catalysis. Dobrinescu C, et.al. Adv. Synth. Catal. 354 , 1301-1306, (2012)
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Synonyms
| 2-Methyl-1,4-naphthalenediol Diacetate |
| MFCD00021469 |
| 2-Methyl-1,4-naphthalenediyl diacetate |
| (4-acetyloxy-3-methylnaphthalen-1-yl) acetate |
| 1,4-Naphthalenediol, 2-methyl-, diacetate |
| Kappaxan (VAN) |
| 2-Methylnaphthalene-1,4-diyl diacetate |
| EINECS 209-352-1 |
| Vitamin K4 |
