CAS 51-20-7|5-Bromouracil
Introduction：Basic information about CAS 51-20-7|5-Bromouracil, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5-Bromouracil | ||
|---|---|---|---|
| CAS Number | 51-20-7 | Molecular Weight | 190.98 |
| Density | 2.0±0.1 g/cm3 | Boiling Point | 384ºC |
| Molecular Formula | C4H3BrN2O2 | Melting Point | >300 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | / |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 5-bromouracil |
|---|---|
| Synonym | More Synonyms |
5-Bromouracil BiologicalActivity
| Description | 5-Bromouracil is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
|---|---|
| Related Catalog | Research Areas >>Others |
| In Vitro | 5-溴尿嘧啶通过诱导 A 型样 DNA 破坏核小体定位。 |
Chemical & Physical Properties
| Density | 2.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 384ºC |
| Melting Point | >300 °C(lit.) |
| Molecular Formula | C4H3BrN2O2 |
| Molecular Weight | 190.98 |
| Exact Mass | 189.937775 |
| PSA | 65.72000 |
| LogP | -0.35 |
| Index of Refraction | 1.590 |
| InChIKey | LQLQRFGHAALLLE-UHFFFAOYSA-N |
| SMILES | O=c1[nH]cc(Br)c(=O)[nH]1 |
| Water Solubility | SOLUBLE IN COLD WATER |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1700 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1400 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 5 gm/kg/2W-I
- TOXIC EFFECTS :
- Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 400 mg/kg
- SEX/DURATION :
- female 12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4 per # born alive)
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
MUTATION DATA - TEST SYSTEM :
- Insect - grasshopper
- DOSE/DURATION :
- 10 mg
- REFERENCE :
- IDZAAW Japanese Journal of Genetics. Idengaku Zasshi. (Genetics Soc. of Japan, 111 Tanida, Mishima, Shizuoka-ken, Japan) V.1- 1921- Volume(issue)/page/year: 38,305,1963
- TEST SYSTEM :
- Insect - grasshopper
- DOSE/DURATION :
- 10 mg
- REFERENCE :
- IDZAAW Japanese Journal of Genetics. Idengaku Zasshi. (Genetics Soc. of Japan, 111 Tanida, Mishima, Shizuoka-ken, Japan) V.1- 1921- Volume(issue)/page/year: 38,305,1963
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R46 |
| Safety Phrases | S36/37-S53-S45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | YQ9060000 |
| HS Code | 29335995 |
Customs
| HS Code | 2933599090 |
|---|---|
| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| Uracil,5-bromo |
| 2,4(1H,3H)-Pyrimidinedione, 5-bromo- |
| Bromouracil |
| 5-Bromo-2,4(1H,3H)-pyrimidinedione |
| 5-bromo-uraci |
| 5-bromopyrimidine-2,4-diol |
| 5-bromo-2,4-dioxopyrimidine |
| 5-Bromouracil |
| 5-BrUra |
| 5-Br-uracil |
| BROMOURACIL,5 |
| 5-bromo-uracil |
| EINECS 200-084-0 |
| MFCD00006017 |
| 5-bromopyrimidine-2,4(1H,3H)-dione |
