CAS 120202-66-6|Clopidogrel bisulfate

Introduction：Basic information about CAS 120202-66-6|Clopidogrel bisulfate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Clopidogrel bisulfate BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Articles16
7. Synonyms

Common Name	Clopidogrel bisulfate
CAS Number	120202-66-6	Molecular Weight	419.900
Density	/	Boiling Point	423.7ºC at 760 mmHg
Molecular Formula	C₁₆H₁₈ClNO₆S₂	Melting Point	184ºC
MSDS	ChineseUSA	Flash Point	210ºC

Names

Name	clopidogrel sulfate
Synonym	More Synonyms

Clopidogrel bisulfate BiologicalActivity

Description	Clopidogrel is an antiplatelet agent which works by blocking platelets from sticking together and prevents them from forming harmful clots.
Related Catalog	Signaling Pathways >>GPCR/G Protein >>P2Y ReceptorResearch Areas >>Cardiovascular Disease
References	[1]. Geiger, J., et al., Specific impairment of human platelet P2Y(AC) ADP receptor-mediated signaling by the antiplatelet drug clopidogrel. Arterioscler Thromb Vasc Biol, 1999. 19(8): p. 2007-11. [2]. Roald, H.E., et al., Clopidogrel--a platelet inhibitor which inhibits thrombogenesis in non-anticoagulated human blood independently of the blood flow conditions. Thromb Haemost, 1994. 71(5): p. 655-62. [3]. Ramadan, R., et al., Effects of Clopidogrel Therapy on Oxidative Stress, Inflammation, Vascular Function and Progenitor Cells in Stable Coronary Artery Disease. J Cardiovasc Pharmacol, 2013.

Description

Clopidogrel is an antiplatelet agent which works by blocking platelets from sticking together and prevents them from forming harmful clots.

Related Catalog

Signaling Pathways >>GPCR/G Protein >>P2Y ReceptorResearch Areas >>Cardiovascular Disease

References

[1]. Geiger, J., et al., Specific impairment of human platelet P2Y(AC) ADP receptor-mediated signaling by the antiplatelet drug clopidogrel. Arterioscler Thromb Vasc Biol, 1999. 19(8): p. 2007-11.

[2]. Roald, H.E., et al., Clopidogrel--a platelet inhibitor which inhibits thrombogenesis in non-anticoagulated human blood independently of the blood flow conditions. Thromb Haemost, 1994. 71(5): p. 655-62.

[3]. Ramadan, R., et al., Effects of Clopidogrel Therapy on Oxidative Stress, Inflammation, Vascular Function and Progenitor Cells in Stable Coronary Artery Disease. J Cardiovasc Pharmacol, 2013.

Chemical & Physical Properties

Boiling Point	423.7ºC at 760 mmHg
Melting Point	184ºC
Molecular Formula	C₁₆H₁₈ClNO₆S₂
Molecular Weight	419.900
Flash Point	210ºC
Exact Mass	419.026398
PSA	140.76000
LogP	3.96550
Appearance of Characters	solid \| white
InChIKey	FDEODCTUSIWGLK-RSAXXLAASA-N
SMILES	COC(=O)C(c1ccccc1Cl)N1CCc2sccc2C1.O=S(=O)(O)O
Storage condition	2-8°C
Water Solubility	DMSO: ~26 mg/mL

Safety Information

Hazard Codes	Xi
Safety Phrases	22-24/25
RIDADR	UN 1759
WGK Germany	3
Packaging Group	II
Hazard Class	8
HS Code	2942000000

Customs

HS Code	2942000000

Articles16

Environmental friendly method for urban wastewater monitoring of micropollutants defined in the Directive 2013/39/EU and Decision 2015/495/EU.

J. Chromatogr. A. 1418 , 140-9, (2015)

The fate and removal of organic micropollutants in the environment is a demanding issue evidenced by the recent European policy. This work presents an analytical method for the trace quantification of...

RASA3 is a critical inhibitor of RAP1-dependent platelet activation.

J. Clin. Invest. 125(4) , 1419-32, (2015)

The small GTPase RAP1 is critical for platelet activation and thrombus formation. RAP1 activity in platelets is controlled by the GEF CalDAG-GEFI and an unknown regulator that operates downstream of t...

Comparison of substrate specificity among human arylacetamide deacetylase and carboxylesterases.

Eur. J. Pharm. Sci. 78 , 47-53, (2015)

Human arylacetamide deacetylase (AADAC) is an esterase responsible for the hydrolysis of some drugs, including flutamide, indiplon, phenacetin, and rifamycins. AADAC is highly expressed in the human l...

Synonyms

Methyl (S)-(+)-2-(2-Chlorophenyl)-2-[6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl]acetate Sulfate

MFCD00876395

Plavix

Clopidogrel sulfate

Clopidogrel Hydrogen sulfate

Methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate

methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoate sulfate

methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoate sulfate (1:1)

Clopidogrel bisulfate

(S)-(+)-Clopidogrel Sulfate

(2S)-(2-chlorophényl)(6,7-dihydrothiéno[3,2-c]pyridin-5(4H)-yl)éthanoate de méthyle sulfate

Clopidogrel Hydrogensulfate

Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (αS)-, sulfate (1:1)

(+)-Clopidogrel hydrogen sulfate

Clopidogrel bisulphate

(S)-(+)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyrid-5-yl)acetate bisulfate

Methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate sulfate (1:1)

a-(S)-(2-Chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetic Acid Methyl Ester Sulfate (1:1)

Methyl aS-(2-Chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetate Sulfate (1:1)

Methyl-(2S)-(2-chlorphenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoatsulfat

Clopidogrel

(S)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate hydrogensulfate

S-(+)-Clopidogrel Hydrogen Sulfate

Clopidogrel (hydrogen sulfate)

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