Introduction：Basic information about CAS 40580-83-4|HARMOL HYDROCHLORIDE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | HARMOL HYDROCHLORIDE |
|---|
| CAS Number | 40580-83-4 | Molecular Weight | 234.68200 |
|---|
| Density | / | Boiling Point | 552.7ºC at 760 mmHg |
|---|
| Molecular Formula | C12H11ClN2O | Melting Point | / |
|---|
| MSDS | / | Flash Point | 255ºC |
|---|
Names
| Name | harmol hydrochloride |
|---|
| Synonym | More Synonyms |
|---|
Chemical & Physical Properties
| Boiling Point | 552.7ºC at 760 mmHg |
|---|
| Molecular Formula | C12H11ClN2O |
|---|
| Molecular Weight | 234.68200 |
|---|
| Flash Point | 255ºC |
|---|
| Exact Mass | 234.05600 |
|---|
| PSA | 48.91000 |
|---|
| LogP | 3.53210 |
|---|
| InChIKey | RBOUBJPHXSVUTH-UHFFFAOYSA-N |
|---|
| SMILES | Cc1[nH]ccc2c1[nH]c1cc(=O)ccc12.Cl |
|---|
Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- UV1048000
- CHEMICAL NAME :
- 9H-Pyrido(3,4-b)indol-7-ol, 1-methyl-, hydrochloride
- CAS REGISTRY NUMBER :
- 40580-83-4
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C12-H10-N2-O.Cl-H
- MOLECULAR WEIGHT :
- 234.70
- WISWESSER LINE NOTATION :
- T B656 EN HMJ F1 KQ &GH
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 4,33,1931
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 140 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 4,33,1931
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Cardiac - pulse rate increase, without fall in BP Cardiac - pulse rate
- REFERENCE :
- QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 4,33,1931
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 280 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 4,33,1931
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - ataxia Cardiac - cardiomyopathy including infarction
- REFERENCE :
- QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 4,33,1931
|
Safety Information
| Safety Phrases | S24/25 |
|---|
| HS Code | 2933990090 |
|---|
Customs
| HS Code | 2933990090 |
|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
|---|
Synonyms
| Harmol hydrochloride monohydrate |
| EINECS 254-980-1 |
| HARMOL HCL |
