CAS 57078-99-6|5-Maleimidovaleric acid

Introduction：Basic information about CAS 57078-99-6|5-Maleimidovaleric acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 5-Maleimidovaleric acid BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	5-Maleimidovaleric acid
CAS Number	57078-99-6	Molecular Weight	197.188
Density	1.3±0.1 g/cm3	Boiling Point	400.7±28.0 °C at 760 mmHg
Molecular Formula	C₉H₁₁NO₄	Melting Point	/
MSDS	/	Flash Point	196.2±24.0 °C

Names

Name	5-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanoic acid
Synonym	More Synonyms

5-Maleimidovaleric acid BiologicalActivity

Description	5-Maleimidovaleric acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	400.7±28.0 °C at 760 mmHg
Molecular Formula	C₉H₁₁NO₄
Molecular Weight	197.188
Flash Point	196.2±24.0 °C
Exact Mass	197.068802
PSA	74.68000
LogP	0.56
Vapour Pressure	0.0±2.0 mmHg at 25°C
Index of Refraction	1.544
InChIKey	ACVAAFHNDGTZLL-UHFFFAOYSA-N
SMILES	O=C(O)CCCCN1C(=O)C=CC1=O

Safety Information

Hazard Codes	Xi
HS Code	2925190090

Customs

HS Code	2925190090
Summary	2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Synonyms

5-(2,5-dioxopyrrol-1-yl)pentanoic acid

5-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanoic acid

1H-Pyrrole-1-pentanoic acid, 2,5-dihydro-2,5-dioxo-

5-Maleimidovaleric acid

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