Introduction：Basic information about CAS 57014-02-5|Calcitonin, eel, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Calcitonin, eel is the thyroid hormone peptide that contributes to the regulation of calcium homeostasis, widely used in the research of postmenopausal osteoporosis.
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Signaling Pathways >>Others >>OthersPeptidesResearch Areas >>Others
In Vitro
Calcitonin, eel effectively induces a concentration-dependent stimulation of phosphoinositide hydrolysis and stimulates prolactin release compared to salmon calcitonin in cultured anterior pituitary cells. However, Calcitonin, eel is inactive on the inhibition of prolactin release under thyrotropin releasing hormone (TRH) stimulated conditions[1].
References
[1]. Sortino MA, et al. Comparative effects of eel calcitonin, salmon calcitonin and [Asu1,7]eel calcitonin on hypophyseal and osteoblastic function. Gynecol Endocrinol. 1993 Jun;7(2):89-96.
The role of peptides and receptors of the calcitonin family in the regulation of bone metabolism.
Bone 43 , 813-818, (2008)
The 'calcitonin family' is a group of peptide hormones that share structural similarities with calcitonin, and includes calcitonin gene-related peptide (CGRP), amylin, adrenomedullin and adrenomedulli...
Signal transduction pathways of calcitonin/calcitonin receptor regulating cytoskeletal organization and bone-resorbing activity of osteoclasts.
Cell Mol. Biol. 52 , 19-23, (2006)
Calcitonin is a calcium-regulating peptide hormone that acts directly on osteoclasts and suppresses their function. In this review we will focus on the downstream signaling pathways of calcitonin rece...
Back to the future: revisiting parathyroid hormone and calcitonin control of bone remodeling.
Horm. Metab. Res. 42 , 299-306, (2010)
This review reflects on the past, present, and future of translational research on calcitropic hormones and bone metabolism. Calcitonin (CT) and parathormone (PTH) are complementary hormones involved ...
