CAS 1113-83-3|N-Glycolylneuraminic acid

Introduction:Basic information about CAS 1113-83-3|N-Glycolylneuraminic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameN-Glycolylneuraminic acid
CAS Number1113-83-3Molecular Weight325.269
Density1.9±0.1 g/cm3Boiling Point826.1±75.0 °C at 760 mmHg
Molecular FormulaC11H19NO10Melting Point188-190°C
MSDSChineseUSAFlash Point453.4±37.1 °C

Names

NameN-glycoloyl-β-neuraminic acid
SynonymMore Synonyms

N-Glycolylneuraminic acid BiologicalActivity

DescriptionN-Glycolylneuraminic acid is a nonhuman sialic acid molecule synthesized in pigs but not in humans. N-Glycolylneuraminic acid works as a decoy receptor of N-Glycolylneuraminic acid-binding influenza A viruses (IAVs)[1].
Related CatalogSignaling Pathways >>Anti-infection >>Influenza VirusResearch Areas >>Inflammation/Immunology
References

[1]. Takahashi T, et al. N-glycolylneuraminic acid on human epithelial cells prevents entry of influenza A viruses that possess N-glycolylneuraminic acid binding ability. J Virol. 2014 Aug;88(15):8445-56.

Chemical & Physical Properties

Density1.9±0.1 g/cm3
Boiling Point826.1±75.0 °C at 760 mmHg
Melting Point188-190°C
Molecular FormulaC11H19NO10
Molecular Weight325.269
Flash Point453.4±37.1 °C
Exact Mass325.100891
PSA197.01000
LogP-2.96
Vapour Pressure0.0±0.6 mmHg at 25°C
Index of Refraction1.651
InChIKeyFDJKUWYYUZCUJX-AJKRCSPLSA-N
SMILESO=C(CO)NC1C(O)CC(O)(C(=O)O)OC1C(O)C(O)CO
Storage condition−20°C

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard CodesXi
RIDADRNONH for all modes of transport
WGK Germany3

Articles44

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Determination of sialic acids in milks and milk-based products.

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Sialic acids are becoming recognized as important components of milk-based products for infants and young children. As such, many companies now label the sialic acid content of their products. To cont...

Production of monoclonal antibodies directed to Hanganutziu-Deicher active gangliosides, N-glycolylneuraminic acid-containing gangliosides.

J. Biochem. 117(5) , 1062-9, (1995)

We have established three kinds of monoclonal antibodies against gangliosides containing N-glycolylneuraminic acid (NeuGc) by immunization of BALB/c mice with the purified gangliosides inserted into l...

Synonyms

D-glycero-β-D-galacto-2-Nonulopyranosonic acid, 3,5-dideoxy-5-[[(1E)-1,2-dihydroxyethylidene]amino]-
Neuraminic acid, N-glycolyl-
(6R)-3,5-Dideoxy-5-(glycoloylamino)-6-[(1R,2R)-1,2,3-trihydroxypropyl]-α-L-threo-hex-2-ulopyranosonic acid
NGNA
NeuNGl
N-Glycolylneuraminate
(6R)-3,5-Dideoxy-5-[(E)-(1,2-dihydroxyethylidene)amino]-6-[(1R,2R)-1,2,3-trihydroxypropyl]-α-L-threo-hex-2-ulopyranosonic acid
5-Glykoloylamino-D-glycero-D-galacto-3,5-didesoxy-[2]nonulonsaeure
N-glycoloyl-β-neuraminic acid
N-GLYCOLYNEURAMINIC ACID
GcNeu
N-Glycolyl Neuraminic Acid
MFCD00057551
N-glycoylneuraminic acid
N-glycoloyl-neuraminic acid
N-Glycolylneuraminic Acid (200 mg)
N-glycoloyl-beta-neuraminic acid
N-Glykoloyl-neuraminsaeure
Glycolylneuraminic Aci
N-Glykolyl-neuraminsaeure
Neu5Glc NeuNGl
Neu5Glc,NeuNGl
Neu5Gc
Glycolylneuraminic Acid
N-GLYCOLYLNEURAMINIC ACID FROM PORCINE*SUBMAXILLARY
D-glycero-β-D-galacto-2-Nonulopyranosonic acid, 3,5-dideoxy-5-[(2-hydroxyacetyl)amino]-
N-(2-Hydroxyacetyl)-neuraminic Acid
3,5-Dideoxy-5-(glycoloylamino)-D-glycero-β-D-galacto-non-2-ulopyranosonic acid
N-(Hydroxyacetyl)neuraminic acid
N-Glycolylneuraminic acid
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