CAS 120-43-4|N-Carbethoxy Piperazine

Introduction：Basic information about CAS 120-43-4|N-Carbethoxy Piperazine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles1
7. Synonyms

Common Name	N-Carbethoxy Piperazine
CAS Number	120-43-4	Molecular Weight	158.198
Density	1.1±0.1 g/cm3	Boiling Point	237.0±15.0 °C at 760 mmHg
Molecular Formula	C₇H₁₄N₂O₂	Melting Point	120 °C
MSDS	ChineseUSA	Flash Point	97.1±20.4 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	Ethyl N-piperazinecarboxylate
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	237.0±15.0 °C at 760 mmHg
Melting Point	120 °C
Molecular Formula	C₇H₁₄N₂O₂
Molecular Weight	158.198
Flash Point	97.1±20.4 °C
Exact Mass	158.105530
PSA	41.57000
LogP	-0.14
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.467
InChIKey	LNOQURRKNJKKBU-UHFFFAOYSA-N
SMILES	CCOC(=O)N1CCNCC1
Water Solubility	soluble

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TL1378000

CHEMICAL NAME :: 1-Piperazinecarboxylic acid, ethyl ester

CAS REGISTRY NUMBER :: 120-43-4

BEILSTEIN REFERENCE NO. :: 0125780

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C7-H14-N2-O2

MOLECULAR WEIGHT :: 158.23

WISWESSER LINE NOTATION :: T6M DNTJ AVO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 138 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - muscle contraction or spasticity

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 33,825,1987

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xn:Harmful;
Risk Phrases	R22;R36/37/38
Safety Phrases	S23-S24/25-S37/39-S26
RIDADR	UN 2810 6.1/PG 3
WGK Germany	3
RTECS	TL1378000
Packaging Group	III
Hazard Class	6.1(b)
HS Code	29335995

Customs

HS Code	2933599090
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles1

Antitumor activity of JS-K [O2-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate] and related O2-aryl diazeniumdiolates in vitro and in vivo.

J. Med. Chem. 49 , 4356-66, (2006)

The literature provides evidence that metabolic nitric oxide (NO) release mediates the cytotoxic activities (against human leukemia and prostate cancer xenografts in mice) of JS-K, a compound of struc...

Synonyms

N-Carbethoxy Piperazine

Ethyl N-Piperazinecarboxylate

1-Piperazinecarboxylic acid, ethyl ester

1-Ethoxycarbonylpiperazine

Ethyl Piperazine-1-Carboxylate

MFCD00005964

1-Piperazinecarboxylic Acid Ethyl Ester

EINECS 204-395-2

Ethyl 1-piperazinecarboxylate

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