CAS 85148-82-9|(S)-4-BENZYL-1,3-THIAZOLIDINE-2-ONE

Introduction:Basic information about CAS 85148-82-9|(S)-4-BENZYL-1,3-THIAZOLIDINE-2-ONE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name(S)-4-BENZYL-1,3-THIAZOLIDINE-2-ONE
CAS Number85148-82-9Molecular Weight211.17100
Density1.596g/cm3Boiling Point479.1ºC at 760 mmHg
Molecular FormulaC9H9NO5Melting Point/
MSDS/Flash Point243.6ºC

Names

Name4-[(S)-amino(carboxy)methyl]-2-hydroxybenzoic acid
SynonymMore Synonyms

(S)-4-BENZYL-1,3-THIAZOLIDINE-2-ONE BiologicalActivity

Description(S)-4C3HPG ((S)-4-Carboxy-3-hydroxyphenylglycine) is an antagonist of metabotropic glutamate receptor 1a (mGluR 1a) and an agonist of GluR2. (S)-4C3HPG has the anticonvulsant activity and protects against audiogenic seizures in DBA/2 mice[1].
Related CatalogSignaling Pathways >>GPCR/G Protein >>mGluRResearch Areas >>Neurological Disease
References

[1]. C Thomsen, et al.  (S)-4-carboxy-3-hydroxyphenylglycine, an antagonist of metabotropic glutamate receptor (mGluR) 1a and an agonist of mGluR2, protects against audiogenic seizures in DBA/2 mice. J Neurochem. 1994 Jun;62(6):2492-5.  

[2]. Thomsen C, et al. (S)-4-carboxy-3-hydroxyphenylglycine, an antagonist of metabotropic glutamate receptor (mGluR) 1a and an agonist of mGluR2, protects against audiogenic seizures in DBA/2 mice. J Neurochem. 1994 Jun;62(6):2492-5.  

Chemical & Physical Properties

Density1.596g/cm3
Boiling Point479.1ºC at 760 mmHg
Molecular FormulaC9H9NO5
Molecular Weight211.17100
Flash Point243.6ºC
Exact Mass211.04800
PSA120.85000
LogP0.87510
Index of Refraction1.675
InChIKeyGXZSAQLJWLCLOX-ZETCQYMHSA-N
SMILESNC(C(=O)O)c1ccc(C(=O)O)c(O)c1

Safety Information

HS Code2922509090

Customs

HS Code2922509090
Summary2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synonyms

Tocris-0320
trans-Triprolidine hydrochloride
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