Introduction：Basic information about CAS 1113-10-6|Guancydine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Guancydine |
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| CAS Number | 1113-10-6 | Molecular Weight | 154.21 |
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| Density | 1.02g/cm3 | Boiling Point | 239.3ºC at 760 mmHg |
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| Molecular Formula | C7H14N4 | Melting Point | / |
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| MSDS | / | Flash Point | 98.5ºC |
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Names
| Name | 1-cyano-2-(2-methylbutan-2-yl)guanidine |
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| Synonym | More Synonyms |
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Guancydine BiologicalActivity
| Description | Guancydine (Guancidine) is an antihypertensive agent[1]. |
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| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>Others |
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| References | [1]. Clark DW, et al. Guancydine: a new antihypertensive agent. Use with quinethazone and guanethidine or propranolol. Ann Intern Med. 1972 Apr;76(4):579-85. |
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Chemical & Physical Properties
| Density | 1.02g/cm3 |
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| Boiling Point | 239.3ºC at 760 mmHg |
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| Molecular Formula | C7H14N4 |
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| Molecular Weight | 154.21 |
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| Flash Point | 98.5ºC |
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| Exact Mass | 154.12200 |
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| PSA | 71.70000 |
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| LogP | 1.65158 |
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| Vapour Pressure | 0.0404mmHg at 25°C |
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| Index of Refraction | 1.504 |
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| InChIKey | VZVGEDRCVUKSEL-UHFFFAOYSA-N |
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| SMILES | CCC(C)(C)N=C(N)NC#N |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- MF0175000
- CHEMICAL NAME :
- Guanidine, 1-cyano-3-tert-pentyl-
- CAS REGISTRY NUMBER :
- 1113-10-6
- LAST UPDATED :
- 199009
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C7-H14-N4
- MOLECULAR WEIGHT :
- 154.25
- WISWESSER LINE NOTATION :
- NCMYUM&MX2&1&1
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 161,88,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 313 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 161,88,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1400 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 161,88,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 322 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 161,88,1968
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Safety Information
Customs
| HS Code | 2926909090 |
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| Summary | HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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Synonyms
| tert.-Amyldicyandiamid |
| Guancydine |
| EINECS 263-799-7 |
| EINECS 214-198-3 |
| Guancidine |
| 1-Cyano-3-t-pentylguanidine |
| Guancydine [USAN] |
| Guancidinum [INN-Latin] |
| 1-Cyano-3-tert-amylguanidine |
| Guancidina [INN-Spanish] |
