Introduction：Basic information about CAS 75689-93-9|Imanixil, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Imanixil |
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| CAS Number | 75689-93-9 | Molecular Weight | 394.35100 |
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| Density | 1.428g/cm3 | Boiling Point | / |
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| Molecular Formula | C17H17F3N6O2 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 4-amino-3-ethoxybenzenesulfonic acid |
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Imanixil BiologicalActivity
| Description | Imanixil (HOE-402 free base) is an inducer of the LDL receptor (LDLR). Imanixil (HOE-402 free base) is also a potent cholesterol-lowering compound, which inhibits very low density-lipoprotein (VLDL) production, and consequently attenuates atherosclerosis development[1]. |
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| Related Catalog | Signaling Pathways >>Others >>Others |
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| References | [1]. Draijer R, et al. HOE 402 lowers serum cholesterol levels by reducing VLDL-lipid production, and not by induction of the LDL receptor, and reduces atherosclerosis in wild-type and LDL receptor-deficient mice. Biochem Pharmacol. 2002 May 1;63(9):1755-61. |
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Chemical & Physical Properties
| Density | 1.428g/cm3 |
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| Molecular Formula | C17H17F3N6O2 |
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| Molecular Weight | 394.35100 |
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| Exact Mass | 394.13700 |
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| PSA | 113.24000 |
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| LogP | 3.68610 |
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| Index of Refraction | 1.601 |
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| InChIKey | FUSNOPLQVRUIIM-UHFFFAOYSA-N |
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| SMILES | CC1(C)CN(c2ncc(C(=O)Nc3cccc(C(F)(F)F)c3)c(N)n2)C(=O)N1 |
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