CAS 121058-88-6|Ac-rC Phosphoramidite

Introduction：Basic information about CAS 121058-88-6|Ac-rC Phosphoramidite, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameAc-rC Phosphoramidite
CAS Number121058-88-6Molecular Weight902.098
Density/Boiling Point/
Molecular FormulaC47H64N5O9PSiMelting Point/
MSDSUSAFlash Point/

Names

NameDMT-2′O-TBDMS-rC(ac) Phosphoramidite
SynonymMore Synonyms

Ac-rC Phosphoramidite BiologicalActivity

DescriptionAc-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA)[1].
Related CatalogSignaling Pathways >>Cell Cycle/DNA Damage >>DNA/RNA SynthesisResearch Areas >>Others
References

[1]. Wipapat Kladwang, et al. Anomalous Reverse Transcription through Chemical Modifications in Polyadenosine Stretches. Biochemistry. 2020 Jun 16;59(23):2154-2170.

Chemical & Physical Properties

Molecular FormulaC47H64N5O9PSi
Molecular Weight902.098
Exact Mass901.421082
PSA169.22000
LogP10.84
InChIKeyQKWKXYVKGFKODW-YOEDQOPESA-N
SMILESCOc1ccc(C(OCC2OC(n3ccc(NC(C)=O)nc3=O)C(O[Si](C)(C)C(C)(C)C)C2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADRNONH for all modes of transport

Synonyms

Ac-rC Phosphoramidite
4-Acetamido-1-{5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-O-[dimethyl(2-methyl-2-propanyl)silyl]-β-L-ribofuranosyl}-2(1H)-pyrimidinone
Ac-rCPhosphoramidite
2(1H)-Pyrimidinone, 4-(acetylamino)-1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-
N-[1-[(2S,3S,4S,5S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide
Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-
N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]cytidine
CAS 59950-55-9|2-tert-butylpyrimidin-5-amine
CAS 149989-68-4|DMT-2′O-TBDMS-rG(tac) Phosphoramidite
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