Introduction:Basic information about CAS 350-12-9|Sulbentine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Sulbentine |
|---|
| CAS Number | 350-12-9 | Molecular Weight | 314.46800 |
|---|
| Density | 1.28g/cm3 | Boiling Point | 451.5ºC at 760mmHg |
|---|
| Molecular Formula | C17H18N2S2 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 226.9ºC |
|---|
Names
| Name | 3,5-dibenzyl-1,3,5-thiadiazinane-2-thione |
|---|
| Synonym | More Synonyms |
|---|
Sulbentine BiologicalActivity
| Description | Sulbentine is an antifungal. |
|---|
| Related Catalog | Signaling Pathways >>Anti-infection >>FungalResearch Areas >>Infection |
|---|
| References | [1]. Thoma K, et al. The photostability of antimycotics. 3. Photostability of locally acting antimycotics. Pharmazie. 1997 May;52(5):362-73. [2]. Hänel H, et al. Evaluation of fungicidal action in vitro and in a skin model considering the influence of penetration kinetics of various standard antimycotics. Ann N Y Acad Sci. 1988;544:329-37. |
|---|
Chemical & Physical Properties
| Density | 1.28g/cm3 |
|---|
| Boiling Point | 451.5ºC at 760mmHg |
|---|
| Molecular Formula | C17H18N2S2 |
|---|
| Molecular Weight | 314.46800 |
|---|
| Flash Point | 226.9ºC |
|---|
| Exact Mass | 314.09100 |
|---|
| PSA | 63.87000 |
|---|
| LogP | 3.81330 |
|---|
| Index of Refraction | 1.705 |
|---|
| InChIKey | QFVAWNPSRQWSDU-UHFFFAOYSA-N |
|---|
| SMILES | S=C1SCN(Cc2ccccc2)CN1Cc1ccccc1 |
|---|
| Storage condition | 2-8℃ |
|---|
Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- XI2772000
- CHEMICAL NAME :
- 2H-1,3,5-Thiadiazine-2-thione, tetrahydro-3,5-dibenzyl-
- CAS REGISTRY NUMBER :
- 350-12-9
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C17-H18-N2-S2
- MOLECULAR WEIGHT :
- 314.49
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 19,558,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. Volume(issue)/page/year: 13,574,1964
|
Safety Information
Customs
| HS Code | 2934999090 |
|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
|---|
Synonyms
| Noticin |
| Refungine |
| Fungiplex |
| Sulbentine |
| Afungin |
| 3-benzyl-5-phenethyltetrahydro-2H-1,3,5-thiadiazine-2-thione |
| Dibenzthione |
| Dibenzthion |
| 3,5-Dibenzyl-tetrahydro-<1,3,5>thiadiazin-2-thion |
| Carbothialdine |
| 3,5-dibenzyl-3,4,5,6-tetrahydro-2H-1,3,5-thiadiazine-2-thione |
| Mecal |
| Dibenzothione |