CAS 350-12-9|Sulbentine

Introduction:Basic information about CAS 350-12-9|Sulbentine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameSulbentine
CAS Number350-12-9Molecular Weight314.46800
Density1.28g/cm3Boiling Point451.5ºC at 760mmHg
Molecular FormulaC17H18N2S2Melting Point/
MSDS/Flash Point226.9ºC

Names

Name3,5-dibenzyl-1,3,5-thiadiazinane-2-thione
SynonymMore Synonyms

Sulbentine BiologicalActivity

DescriptionSulbentine is an antifungal.
Related CatalogSignaling Pathways >>Anti-infection >>FungalResearch Areas >>Infection
References

[1]. Thoma K, et al. The photostability of antimycotics. 3. Photostability of locally acting antimycotics. Pharmazie. 1997 May;52(5):362-73.

[2]. Hänel H, et al. Evaluation of fungicidal action in vitro and in a skin model considering the influence of penetration kinetics of various standard antimycotics. Ann N Y Acad Sci. 1988;544:329-37.

Chemical & Physical Properties

Density1.28g/cm3
Boiling Point451.5ºC at 760mmHg
Molecular FormulaC17H18N2S2
Molecular Weight314.46800
Flash Point226.9ºC
Exact Mass314.09100
PSA63.87000
LogP3.81330
Index of Refraction1.705
InChIKeyQFVAWNPSRQWSDU-UHFFFAOYSA-N
SMILESS=C1SCN(Cc2ccccc2)CN1Cc1ccccc1
Storage condition2-8℃

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XI2772000
CHEMICAL NAME :
2H-1,3,5-Thiadiazine-2-thione, tetrahydro-3,5-dibenzyl-
CAS REGISTRY NUMBER :
350-12-9
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C17-H18-N2-S2
MOLECULAR WEIGHT :
314.49

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 19,558,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. Volume(issue)/page/year: 13,574,1964

Safety Information

HS Code2934999090

Customs

HS Code2934999090
Summary2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

Noticin
Refungine
Fungiplex
Sulbentine
Afungin
3-benzyl-5-phenethyltetrahydro-2H-1,3,5-thiadiazine-2-thione
Dibenzthione
Dibenzthion
3,5-Dibenzyl-tetrahydro-<1,3,5>thiadiazin-2-thion
Carbothialdine
3,5-dibenzyl-3,4,5,6-tetrahydro-2H-1,3,5-thiadiazine-2-thione
Mecal
Dibenzothione
CAS 55311-94-9|2-chloro-4-methyl-benzenesulfonyl chloride
CAS 6425-41-8|Morpholine,4-cyclohexyl-
Recommended......
TOP