CAS 1486-70-0|3-O-Methylquercetin
Introduction：Basic information about CAS 1486-70-0|3-O-Methylquercetin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 3-O-Methylquercetin | ||
|---|---|---|---|
| CAS Number | 1486-70-0 | Molecular Weight | 316.262 |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 643.0±55.0 °C at 760 mmHg |
| Molecular Formula | C16H12O7 | Melting Point | / |
| MSDS | USA | Flash Point | 244.7±25.0 °C |
| Symbol | GHS06 | Signal Word | Danger |
Names
| Name | 3',4',5,7-tetrahydroxy-3-methoxyflavone |
|---|---|
| Synonym | More Synonyms |
3-O-Methylquercetin BiologicalActivity
| Description | 3-O-Methylquercetin (3-MQ), a main constituent of Rhamnus nakaharai, inhibits total cAMP and cGMP-phosphodiesterase (PDE) of guinea pig trachealis. 3-O-Methylquercetin (3-MQ) exhibits IC50 values of 31.9 μM， 86.9 μM， 18.6 μM and 1.6 μM for PDE1, PDE5, PDE2 and PDE4, respectively[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Metabolic Enzyme/Protease >>Phosphodiesterase (PDE)Research Areas >>Inflammation/Immunology |
| References | [1]. Wun-Chang Ko, et al. 3-O-methylquercetin More Selectively Inhibits Phosphodiesterase Subtype 3. Planta Med. 2003 Apr;69(4):310-5. |
Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 643.0±55.0 °C at 760 mmHg |
| Molecular Formula | C16H12O7 |
| Molecular Weight | 316.262 |
| Flash Point | 244.7±25.0 °C |
| Exact Mass | 316.058289 |
| PSA | 120.36000 |
| LogP | 2.02 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.762 |
| InChIKey | WEPBGSIAWZTEJR-UHFFFAOYSA-N |
| SMILES | COc1c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c2c1=O |
Safety Information
| Symbol | GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 |
| Hazard Codes | T |
| Risk Phrases | 25 |
| Safety Phrases | 45 |
| RIDADR | UN 2811 6.1 / PGIII |
| HS Code | 2914509090 |
Customs
| HS Code | 2914509090 |
|---|---|
| Summary | HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
Articles8
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| Biologically active constituents of Centipeda minima: isolation of a new plenolin ester and the antiallergy activity of sesquiterpene lactones. Chem. Pharm. Bull. 33(9) , 4091-4, (1985) | |
| Isolation of flavonoids and a chalcone from Helichrysum odoratissimum and synthesis of helichrysetin. J. Nat. Prod. 52(3) , 629-33, (1989) 3,5-Dihydroxy-6,7,8-trimethoxyflavone, 3-O-methylquercetin, and helichrysetin were isolated from the flowers of the Rwandese medicinal plant, Helichrysum odoratissimum. Because of inconsistencies of t... |
Synonyms
| 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-methoxychromen-4-one |
| 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-4H-chromen-4-one |
| 3-methoxy-5,7,3',4'-tetrahydroxy-flavone |
| 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-4H-1-benzopyran-4-one |
| 3-O-Methylquercetin |
| 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-methoxy- |
