CAS 123-41-1|Choline Hydroxide

Introduction:Basic information about CAS 123-41-1|Choline Hydroxide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameCholine Hydroxide
CAS Number123-41-1Molecular Weight121.178
Density1.09 g/mL at 20 °CBoiling Point/
Molecular FormulaC5H15NO2Melting Point/
MSDS/Flash Point92 °F

Names

Name2-Hydroxyethyltrimethylammonium Hydroxide
SynonymMore Synonyms

Choline Hydroxide BiologicalActivity

DescriptionCholine hydroxide is a Choline hydrogen oxidized derivative and a strong organic base, can be used as the standard alkaline to adjust the pH of the medium. Choline is an orally active nutrient, serves as an important component of lecithin and sphingomyelin, promotes fat metabolism [1][2][3].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
In VitroCholine hydroxide can be used as the standard alkaline, and (0.5 M) results pHo shifts rapidly to 7.59 in a sucrose medium (pH at 7.08)[1]. Choline hydroxide (0.1-0.5 g/mL), together with organic carboxylic acids, makes preparation of ionic liquids, which is used for prepare a ionic liquid-reverse micelle drug-carrying delivery system and involves in epidermal desensitization research[2].
References

[1]. Mitchell P, et al. Estimation of membrane potential and pH difference across the cristae membrane of rat liver mitochondria. Eur J Biochem. 1969 Feb;7(4):471-84.

[2]. Ding Y, et al. An ionic liquid-reverse micelle drug delivery system for epidermal desensitization therapy and its preparation method and application: China, CN113975224. 2022-01-28.

[3]. Wang F, et al. Short communication: Effects of dietary deoiled soy lecithin supplementation on circulating choline and choline metabolites, and the plasma phospholipid profile in Holstein cows fed palm fat. J Dairy Sci. 2021 Feb;104(2):1838-1845.

Chemical & Physical Properties

Density1.09 g/mL at 20 °C
Molecular FormulaC5H15NO2
Molecular Weight121.178
Flash Point92 °F
Exact Mass121.110275
PSA43.29000
Index of Refractionn20/D 1.4304
InChIKeyKIZQNNOULOCVDM-UHFFFAOYSA-M
SMILESC[N+](C)(C)CCO.[OH-]
Storage condition2-8°C
StabilityStable. Combustible. Incompatible with strong oxidizing agents.
Water Solubilitymiscible

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GA4025500
CHEMICAL NAME :
Choline hydroxide
CAS REGISTRY NUMBER :
123-41-1
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C5-H14-N-O.H-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
21400 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 23,1357,1968 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1710 No. of Facilities: 31 (estimated) No. of Industries: 1 No. of Occupations: 16 No. of Employees: 11518 (estimated) No. of Female Employees: 5852 (estimated)

Safety Information

Hazard CodesC:Corrosive;
Risk PhrasesR35
Safety PhrasesS26-S36/37/39-S45
RIDADRUN 3286 3/PG 2
WGK Germany1
RTECSGA4025500
Packaging GroupII
Hazard Class8
HS Code2923900090

Customs

HS Code2923900090
Summary2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Synonyms

Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, hydroxide (1:1)
Bursine
Gossypine
Sincaline
VIDINE
MFCD00002831
EINECS 204-625-1
2-Hydroxy-N,N,N-trimethylethanaminium hydroxide
Luridine
Fagine
Choline hydroxide
UNII:7THJ3EG9SY
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