CAS 6730-83-2|Kaurenoic acid
| Common Name | Kaurenoic acid | ||
|---|---|---|---|
| CAS Number | 6730-83-2 | Molecular Weight | 302.451 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 426.6±34.0 °C at 760 mmHg |
| Molecular Formula | C20H30O2 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 202.8±20.3 °C |
Names
| Name | ent-kaur-16-en-19-oic acid |
|---|---|
| Synonym | More Synonyms |
Kaurenoic acid BiologicalActivity
| Description | Kaurenoic acid is a diterpene from Sphagneticola trilobata, inhibits Inflammatory Pain by the inhibition of cytokine production and activation of the NO–cyclic GMP–PKG–ATP-sensitive potassium channel signaling pathway[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/ImmunologyResearch Areas >>Neurological Disease |
| References | [1]. Mizokami SS, et al. Kaurenoic acid from Sphagneticola trilobata Inhibits Inflammatory Pain: effect on cytokine production and activation of the NO-cyclic GMP-protein kinase G-ATP-sensitive potassium channel signaling pathway. J Nat Prod. 2012 May 25;75(5):896-904. |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 426.6±34.0 °C at 760 mmHg |
| Molecular Formula | C20H30O2 |
| Molecular Weight | 302.451 |
| Flash Point | 202.8±20.3 °C |
| Exact Mass | 302.224579 |
| PSA | 37.30000 |
| LogP | 6.37 |
| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
| Index of Refraction | 1.550 |
| InChIKey | NIKHGUQULKYIGE-SHAPNJEPSA-N |
| SMILES | C=C1CC23CCC4C(C)(C(=O)O)CCCC4(C)C2CCC1C3 |
| Storage condition | ?20°C |
Safety Information
| RIDADR | NONH for all modes of transport |
|---|
Articles25
More Articles| Development and validation of two methods based on high-performance liquid chromatography-tandem mass spectrometry for determining 1,2-benzopyrone, dihydrocoumarin, o-coumaric acid, syringaldehyde and kaurenoic acid in guaco extracts and pharmaceutical preparations. J. Sep. Sci. 34(7) , 740-8, (2011) In this study, two HPLC-ESI-MS/MS methods were developed and validated for the determination of 1,2-benzopyrone (COU), o-coumaric acid (OCA), kaurenoic acid (KAU), syringaldehyde (SYR), and dihydrocou... | |
| Anticonvulsant effect of kaurenoic acid isolated from the root bark of Annona senegalensis. Pharmacol. Biochem. Behav. 109 , 38-43, (2013) The herbal preparations of Annona senegalensis Pers. (Annonaceae) root bark are used in Nigerian ethnomedicine for the treatment of epilepsy and febrile seizures. The scientific evidence for this effe... | |
| Biosynthesis of uterotonic diterpenes from Montanoa tomentosa (zoapatle). J. Plant Physiol. 166(18) , 1961-7, (2009) Montanoa tomentosa (zoapatle) is a Central American plant used in Mexico in traditional herbal medicine to ease childbirth labor and to cure certain female disorders. Recently, crude extracts of M. to... |
Synonyms
| Kaurenoic acid |
| Cunabic acid |
| (5β,8α,9β,10α,13α)-Kaur-16-en-18-oic acid |
| (5β,8α,9β,10α)-Kaur-16-en-18-oic acid |
| KAUREN-19-OIC ACID |
| Kaurane-16-ene-18-oic acid |
| ent-kaur-16-en-19-oic acid |
