CAS 683-57-8|2-Bromoacetamide
Introduction：Basic information about CAS 683-57-8|2-Bromoacetamide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-Bromoacetamide | ||
|---|---|---|---|
| CAS Number | 683-57-8 | Molecular Weight | 137.963 |
| Density | 1.8±0.1 g/cm3 | Boiling Point | 271.6±23.0 °C at 760 mmHg |
| Molecular Formula | C2H4BrNO | Melting Point | 87-91 °C(lit.) |
| MSDS | USA | Flash Point | 118.1±22.6 °C |
| Symbol | GHS05, GHS06 | Signal Word | Danger |
Names
| Name | 2-Bromoacetamide |
|---|---|
| Synonym | More Synonyms |
2-Bromoacetamide BiologicalActivity
| Description | 2-Bromoacetamide can inactivate alcohol dehydrogenase[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
| References | [1]. Fries RW, et al. Activation of liver alcohol dehydrogenases by imidoesters generated in solution. Biochemistry. 1975;14(23):5233‐5238. |
Chemical & Physical Properties
| Density | 1.8±0.1 g/cm3 |
|---|---|
| Boiling Point | 271.6±23.0 °C at 760 mmHg |
| Melting Point | 87-91 °C(lit.) |
| Molecular Formula | C2H4BrNO |
| Molecular Weight | 137.963 |
| Flash Point | 118.1±22.6 °C |
| Exact Mass | 136.947617 |
| PSA | 43.09000 |
| LogP | -0.52 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.511 |
| InChIKey | JUIKUQOUMZUFQT-UHFFFAOYSA-N |
| SMILES | NC(=O)CBr |
| Storage condition | Store at RT. |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 124 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YHTPAD Yaoxue Tongbao. Bulletin of Pharmacology. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.13-23, 1978-88. For publisher information, see ZYZAEU. Volume(issue)/page/year: 16(8),54,1981
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- >102 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YHTPAD Yaoxue Tongbao. Bulletin of Pharmacology. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.13-23, 1978-88. For publisher information, see ZYZAEU. Volume(issue)/page/year: 16(8),54,1981
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 61 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YHTPAD Yaoxue Tongbao. Bulletin of Pharmacology. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.13-23, 1978-88. For publisher information, see ZYZAEU. Volume(issue)/page/year: 16(8),54,1981
Safety Information
| Symbol | GHS05, GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H314 |
| Precautionary Statements | P280-P301 + P310-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | T,C |
| Risk Phrases | R25;R34 |
| Safety Phrases | S26-S27-S36/37/39-S45 |
| RIDADR | UN 2923 8/PG 2 |
| WGK Germany | 3 |
| RTECS | AB4587000 |
| Packaging Group | III |
| Hazard Class | 8 |
| HS Code | 2924199013 |
Customs
| HS Code | 2924199013 |
|---|---|
| Summary | HS:2924199013 2-bromoacetamide VAT:17.0% Tax rebate rate:0.0% Supervision conditions:S MFN tariff:6.5% General tariff:30.0% |
Articles4
More Articles| Carborane-derived local anesthetics are isomer dependent. ChemMedChem 10(1) , 62-7, (2014) Clinically there is a need for local anesthetics with a greater specificity of action on target cells and longer duration. We have synthesized a series of local anesthetic derivatives we call boronica... | |
| (N)-methanocarba 2,N6-disubstituted adenine nucleosides as highly potent and selective A3 adenosine receptor agonists. J. Med. Chem. 48(6) , 1745-58, (2005) A series of ring-constrained (N)-methanocarba-5'-uronamide 2,N(6)-disubstituted adenine nucleosides have been synthesized via Mitsunobu condensation of the nucleobase precursor with a pseudosugar ring... | |
| Kinetic analysis of sequence-specific alkylation of DNA by pyrimidine oligodeoxyribonucleotide-directed triple-helix formation. Bioconjug. Chem. 8(3) , 354-64, (1997) Attachment of a nondiffusible bromoacetyl electrophile to the 5-position of a thymine at the 5'-end of a pyrimidine oligodeoxyribonucleotide affords sequence-specific alkylation of a guanine base in d... |
Synonyms
| Bromoacetamide |
| EINECS 226-270-1 |
| Acetamide, 2-bromo- |
| MFCD00008025 |
| 2-Bromoacetamide |
