Introduction：Basic information about CAS 19179-12-5|Cyclo(Pro-Gly), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Cyclo(Pro-Gly) |
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| CAS Number | 19179-12-5 | Molecular Weight | 154.167 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 447.9±34.0 °C at 760 mmHg |
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| Molecular Formula | C7H10N2O2 | Melting Point | / |
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| MSDS | / | Flash Point | 224.7±25.7 °C |
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Names
| Name | 2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione |
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| Synonym | More Synonyms |
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Cyclo(Pro-Gly) BiologicalActivity
| Description | Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione), an alkaloid isolated from green algae Ulva prolifera, possesses antialgal activity against the common harmful red tide microalgae[1]. Cyclo-(Pro-Gly) (Pyrrolopiperazine-2,5-dione) possesses antiamnesic effects and neuroprotective actions[2]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
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| In Vivo | Cyclo-(Pro-Gly) (0.1 and 10 mg/kg, ip ) seems to be a memory facilitating substance and its presence in rat brain suggests the existence of a new mechanism of memory regulation[3]. |
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| References | [1]. Ying-ying Sun, et al. Isolation, Purification, and Identification of Antialgal Substances in Green Alga Ulva Prolifera for Antialgal Activity Against the Common Harmful Red Tide Microalgae. Environ Sci Pollut Res Int. 2016 Jan;23(2):1449-59. [2]. Fumitaka Hayasaka, et al. Production Method for Cyclic Dipeptide Derived from Native Collagen. Food Science and Technology Research, 22 (4), 477-483, 2016. [3]. T A Gudasheva, et al. Identification of a Novel Endogenous Memory Facilitating Cyclic Dipeptide Cyclo-Prolylglycine in Rat Brain. FEBS Lett. 1996 Aug 5;391(1-2):149-52. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 447.9±34.0 °C at 760 mmHg |
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| Molecular Formula | C7H10N2O2 |
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| Molecular Weight | 154.167 |
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| Flash Point | 224.7±25.7 °C |
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| Exact Mass | 154.074234 |
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| PSA | 52.90000 |
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| LogP | -2.74 |
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| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
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| Index of Refraction | 1.569 |
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| InChIKey | OWOHLURDBZHNGG-UHFFFAOYSA-N |
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| SMILES | O=C1NCC(=O)N2CCCC12 |
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Safety Information
Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| Cyclo-Gly-Pro |
| cyclo-Glycyl-L-Proline |
| DL-2,5-Dioxo-1,4-diazabicyclo<4.3.0>nonane |
| Hexahydropyrrolo[1,2-a]pyrazine-1,4-dione |
| Gly-Pro-diketopiperazine |
| Glycyl-L-proline lactam |
| cyclo-GP |
| cyclo-L-prolylglycine |
| Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro- |
