CAS 201612-66-0|L-Leucine-2-13C

Introduction:Basic information about CAS 201612-66-0|L-Leucine-2-13C, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameL-Leucine-2-13C
CAS Number201612-66-0Molecular Weight132.16600
Density/Boiling Point/
Molecular FormulaC513CH13NO2Melting Point>300ºC(lit.)
MSDSChineseUSAFlash Point/

Names

NameL-Leucine-2-13C
SynonymMore Synonyms

L-Leucine-2-13C BiologicalActivity

DescriptionL-Leucine-2-13C is the 13C-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].
Related CatalogSignaling Pathways >>PI3K/Akt/mTOR >>mTORResearch Areas >>Metabolic Disease
In VitroStable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

Melting Point>300ºC(lit.)
Molecular FormulaC513CH13NO2
Molecular Weight132.16600
Exact Mass132.09800
PSA63.32000
LogP1.14470
InChIKeyROHFNLRQFUQHCH-IJPZVAHNSA-N
SMILESCC(C)CC(N)C(=O)O

Safety Information

RIDADRNONH for all modes of transport
WGK Germany3

Synonyms

MFCD00144627
CAS 201612-61-5|Octanoate-13C sodium
CAS 201740-79-6|Boc-L-Ala-OH-3-13C
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