CAS 202656-13-1|Trometamol(Tris),for molecular biology-d11

Introduction:Basic information about CAS 202656-13-1|Trometamol(Tris),for molecular biology-d11, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameTrometamol(Tris),for molecular biology-d11
CAS Number202656-13-1Molecular Weight132.20300
Density1.137 g/mL at 25ºCBoiling Point219-220ºC10 mm Hg(lit.)
Molecular FormulaC4D11NO3Melting Point162-165ºC(lit.)
MSDSChineseUSAFlash Point/
Symbol
GHS07
Signal WordWarning

Names

NameN,N,1,1,3,3-hexadeuterio-1,3-dideuteriooxy-2-[dideuterio(deuteriooxy)methyl]propan-2-amine
SynonymMore Synonyms

BiologicalActivity

DescriptionTrometamol(Tris),for molecular biology-d11 is the deuterium labeled Trometamol(Tris),for molecular biology[1].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
In VitroStable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

Density1.137 g/mL at 25ºC
Boiling Point219-220ºC10 mm Hg(lit.)
Melting Point162-165ºC(lit.)
Molecular FormulaC4D11NO3
Molecular Weight132.20300
Exact Mass132.14300
PSA86.71000
Index of Refractionn20/D 1.346
InChIKeyLENZDBCJOHFCAS-RNVFPDRBSA-N
SMILESNC(CO)(CO)CO

Safety Information

Symbol
GHS07
Signal WordWarning
Hazard StatementsH315-H319-H335
Precautionary StatementsP261-P305 + P351 + P338
Hazard CodesXi: Irritant;
Risk PhrasesR36/37/38
Safety Phrases26-36
RIDADRNONH for all modes of transport

Synonyms

MFCD00145480
Tris-d11 solution
TRIS-d11
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