Introduction：Basic information about CAS 203645-59-4|Fenitrothion-d6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Fenitrothion-d6 |
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| CAS Number | 203645-59-4 | Molecular Weight | 283.271 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 349.5±52.0 °C at 760 mmHg |
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| Molecular Formula | C9H6D6NO5PS | Melting Point | / |
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| MSDS | / | Flash Point | 165.2±30.7 °C |
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Names
| Name | Fenitrothion-d6 |
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| Synonym | More Synonyms |
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Fenitrothion-d6 BiologicalActivity
| Description | Fenitrothion-d6 is the deuterium labeled Fenitrothion[1]. Fenitrothion, one of the most widely used organophosphorus pesticides, is a cholinesterase inhibiting insecticide/acaricid. Fenitrothion is widely used, as a broad-spectrum insecticide, on cotton crops, vegetables crops, fruit crops, and field crops especially paddy. Fenitrothion leads to accumulation of nitrophenols[2][3]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Neuronal Signaling >>AChE |
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| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
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| References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Abdel-Ghany R, et al. Impact of Exposure to Fenitrothion on Vital Organs in Rats. J Toxicol. 2016;2016:5609734. [3]. Qing Hong, et al. A microcosm study on bioremediation of fenitrothion-contaminated soil using Burkholderia sp. FDS-1. International Biodeterioration & Biodegradation |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 349.5±52.0 °C at 760 mmHg |
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| Molecular Formula | C9H6D6NO5PS |
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| Molecular Weight | 283.271 |
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| Flash Point | 165.2±30.7 °C |
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| Exact Mass | 283.055054 |
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| PSA | 115.41000 |
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| LogP | 3.24 |
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| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
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| Index of Refraction | 1.570 |
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| InChIKey | ZNOLGFHPUIJIMJ-XERRXZQWSA-N |
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| SMILES | COP(=S)(OC)Oc1ccc([N+](=O)[O-])c(C)c1 |
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Synonyms
| O,O-Bis[(H)methyl] O-(3-methyl-4-nitrophenyl) phosphorothioate |
| (3-methyl-4-nitrophenoxy)-sulfanylidene-bis(trideuteriomethoxy)-λ<sup>5</sup>-phosphane |
| Phosphorothioic acid, O,O-dimethyl-d O-(3-methyl-4-nitrophenyl) ester |
