CAS 207569-03-7|1-naphthol-d8

Introduction:Basic information about CAS 207569-03-7|1-naphthol-d8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name1-naphthol-d8
CAS Number207569-03-7Molecular Weight152.21900
Density/Boiling Point/
Molecular FormulaC10D8OMelting Point/
MSDSUSAFlash Point/

Names

Name1-naphthol-d8

1-naphthol-d8 BiologicalActivity

Description1-Naphthol-d8 is the deuterium labeled 1-Naphthol[1]. 1-naphthol is an excited state proton transfer (ESPT) fluorescent molecular probe[2].
Related CatalogResearch Areas >>Others
In VitroStable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Swain J, et al. 1-Naphthol as an ESPT fluorescent molecular probe for sensing thermotropic microenvironmental changes of pluronic F127 in aqueous media. Phys Chem Chem Phys. 2015 Jul 14;17(26):16752-9.  

Chemical & Physical Properties

Molecular FormulaC10D8O
Molecular Weight152.21900
Exact Mass152.10800
PSA20.23000
LogP2.54540
InChIKeyKJCVRFUGPWSIIH-GZORGGLCSA-N
SMILESOc1cccc2ccccc12
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