CAS 80724-20-5|Tetramethylrhodamine-6-isothiocyanate

Introduction：Basic information about CAS 80724-20-5|Tetramethylrhodamine-6-isothiocyanate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Tetramethylrhodamine-6-isothiocyanate BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Tetramethylrhodamine-6-isothiocyanate
CAS Number	80724-20-5	Molecular Weight	443.51800
Density	/	Boiling Point	/
Molecular Formula	C₂₅H₂₁N₃O₃S	Melting Point	/
MSDS	ChineseUSA	Flash Point	/

Names

Name	2-[3-(dimethylamino)-6-dimethylazaniumylidenexanthen-9-yl]-4-isothiocyanatobenzoate
Synonym	More Synonyms

Tetramethylrhodamine-6-isothiocyanate BiologicalActivity

Description	Tetramethylrhodamine-6-isothiocyanate is a potent fluorescent tracer. Tetramethylrhodamine-6-isothiocyanate can be used as an probe for haptenated proteins/peptides for the research of contact allergy. Tetramethylrhodamine-6-isothiocyanate can be used as a tracer for the confocal imaging in living cells[1][2].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
In Vitro	Tetramethylrhodamine-6-isothiocyanate is relatively photostable and robust toward pH changes[1]. Tetramethylrhodamine-6-isothiocyanate as an extreme sensitizer induces a massive cell proliferation and gave an EC3 value of 0.92 mM (0.040%) in the murine LLNA (local lymph node assay)[1]. Tetramethylrhodamine-6-isothiocyanate (1.0 mg; 2h) can used as fluorescence probe for confocal imaging in Fe3O4@PDA incubated living cells[2].
References	[1]. Karlsson I, et al. Peptide Reactivity of Isothiocyanates--Implications for Skin Allergy. Sci Rep. 2016 Feb 17;6:21203. [2]. Yue Q ,et al . A versatile ethanol-mediated polymerization of dopamine for efficient surface modification and the construction of functional core-shell nanostructures. J Mater Chem B. 2013 Nov 28;1(44):6085-6093.

Chemical & Physical Properties

Molecular Formula	C₂₅H₂₁N₃O₃S
Molecular Weight	443.51800
Exact Mass	443.13000
PSA	104.20000
LogP	4.76390
InChIKey	OBYNJKLOYWCXEP-UHFFFAOYSA-N
SMILES	CN(C)c1ccc2c(-c3cc(N=C=S)ccc3C(=O)[O-])c3ccc(=[N+](C)C)cc-3oc2c1
Storage condition	2~8°C

Safety Information

Hazard Codes	Xn: Harmful;

Synonyms

6-TRITC

T3163_SIAL

BIT3022

5(6)-Tetramethylrhodamine isothiocyanate

Tetramethylrhodamine-6-isothiocyanate

Tetramethylrhodamine isothiocyanate

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