Introduction：Basic information about CAS 159912-53-5|Sabcomeline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Sabcomeline |
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| CAS Number | 159912-53-5 | Molecular Weight | 193.24600 |
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| Density | 1.25 | Boiling Point | 278ºC |
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| Molecular Formula | C10H15N3O | Melting Point | / |
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| MSDS | / | Flash Point | 122ºC |
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Names
| Name | (3Z,3R)-N-methoxy-1-azabicyclo[2.2.2]octane-3-carboximidoyl cyanide |
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| Synonym | More Synonyms |
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Sabcomeline BiologicalActivity
| Description | Sabcomeline (SB-202026) is a potent and functionally selective muscarinic M1 receptor partial agonist that improve cognition. Sabcomeline can be used for Alzheimer's disease research[1][2]. |
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| Related Catalog | Signaling Pathways >>Neuronal Signaling >>mAChRSignaling Pathways >>GPCR/G Protein >>mAChRResearch Areas >>Neurological Disease |
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| Target | Muscarinic M1 receptor[1][2] |
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| References | [1]. Hosoi R, et al. Effect of sabcomeline on muscarinic and dopamine receptor binding in intact mouse brain. Ann Nucl Med. 2003;17(2):123-130. [2]. Hatcher JP, et al. Sabcomeline (SB-202026), a functionally selective M1 receptor partial agonist, reverses delay-induced deficits in the T-maze. Psychopharmacology (Berl). 1998;138(3-4):275-282. |
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Chemical & Physical Properties
| Density | 1.25 |
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| Boiling Point | 278ºC |
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| Molecular Formula | C10H15N3O |
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| Molecular Weight | 193.24600 |
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| Flash Point | 122ºC |
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| Exact Mass | 193.12200 |
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| PSA | 48.62000 |
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| LogP | 0.79208 |
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| InChIKey | IQWCBYSUUOFOMF-VIFPVBQESA-N |
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| SMILES | CON=C(C#N)C1CN2CCC1CC2 |
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Safety Information
Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| Sabcomeline |
| Sabcomeline [INN:BAN] |
