Introduction：Basic information about CAS 99-43-4|Oxybuprocaine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Oxybuprocaine |
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| CAS Number | 99-43-4 | Molecular Weight | 308.41600 |
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| Density | 1.052g/cm3 | Boiling Point | 446.9ºC at 760mmHg |
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| Molecular Formula | C17H28N2O3 | Melting Point | / |
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| MSDS | / | Flash Point | 224.1ºC |
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Names
| Name | oxybuprocaine |
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| Synonym | More Synonyms |
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Oxybuprocaine BiologicalActivity
| Description | Oxybuprocaine is a short-acting ester-type local anesthetic agent used in ophthalmology and otolaryngology[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| References | [1]. Masayuki Kohsaka, et al. Oxybuprocaine for apraxia of lid opening in Parkinson's disease: A placebo-controlled pilot trial. Mov Disord |
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Chemical & Physical Properties
| Density | 1.052g/cm3 |
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| Boiling Point | 446.9ºC at 760mmHg |
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| Molecular Formula | C17H28N2O3 |
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| Molecular Weight | 308.41600 |
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| Flash Point | 224.1ºC |
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| Exact Mass | 308.21000 |
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| PSA | 64.79000 |
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| LogP | 3.52750 |
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| Index of Refraction | 1.524 |
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| InChIKey | CMHHMUWAYWTMGS-UHFFFAOYSA-N |
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| SMILES | CCCCOc1cc(C(=O)OCCN(CC)CC)ccc1N |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DG1502000
- CHEMICAL NAME :
- Benzoic acid, 4-amino-3-butoxy-, 2-(diethylamino)ethyl ester
- CAS REGISTRY NUMBER :
- 99-43-4
- BEILSTEIN REFERENCE NO. :
- 2288926
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C17-H28-N2-O3
- MOLECULAR WEIGHT :
- 308.47
- WISWESSER LINE NOTATION :
- 4OR BZ EVO2N2&2
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 37 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AACRAT Anesthesia and Analgesia (New York). (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.36- 1957- Volume(issue)/page/year: 38,265,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AACRAT Anesthesia and Analgesia (New York). (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.36- 1957- Volume(issue)/page/year: 38,265,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 7800 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 3,612,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - quail
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 6,149,1982
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Safety Information
Customs
| HS Code | 2922509090 |
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| Summary | 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| Benoxinate |
| Oxybuprocaine |
| Oxybucaine |
| Prescaina |
| Oxibuprocainum |
| Conjucain |
| 2-(Diethylamino)ethyl 4-amino-3-butoxybenzoate |
| 4-Amino-3-butoxy-benzoesaeure-(2-diaethylamino-aethylester) |
| 4-amino-3-butoxy-benzoic acid-(2-diethylamino-ethyl ester) |
| Benoxil |
| Oxibuprocaina |
| Oxibuprokain |
| Oxyriprocaine |
