CAS 437655-95-3|Fmoc-NH-PEG4-CH2COOH

Introduction:Basic information about CAS 437655-95-3|Fmoc-NH-PEG4-CH2COOH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameFmoc-NH-PEG4-CH2COOH
CAS Number437655-95-3Molecular Weight473.51600
Density/Boiling Point/
Molecular FormulaC25H31NO8Melting Point/
MSDS/Flash Point/

Names

Name1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azaoctadecan-18 -oic acid
SynonymMore Synonyms

Fmoc-NH-PEG4-CH2COOH BiologicalActivity

DescriptionFmoc-NH-PEG4-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC Linker
Target

Cleavable

In VitroADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Maggie Lu, et al. Linker-wirkstoff und antikörper-wirkstoff-konjugat (adc) damit. EP3335734A1.

Chemical & Physical Properties

Molecular FormulaC25H31NO8
Molecular Weight473.51600
Exact Mass473.20500
PSA116.04000
LogP2.88050
InChIKeyXPNLDOFYRFOXLR-UHFFFAOYSA-N
SMILESO=C(O)COCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc21
Storage condition2-8°C

Synonyms

14-methylpentadecyl bromide
14-morpholin-4-yl-daunomycin
14-Morpholino-daunomycin
14-methyl-1-bromopentadecane
Pentadecane,1-bromo-14-methyl
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