Introduction：Basic information about CAS 86811-09-8|Litoxetine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Litoxetine |
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| CAS Number | 86811-09-8 | Molecular Weight | 241.32800 |
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| Density | 1.1g/cm3 | Boiling Point | 387.1ºC at 760 mmHg |
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| Molecular Formula | C16H19NO | Melting Point | / |
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| MSDS | / | Flash Point | 159.2ºC |
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Names
| Name | 4-(naphthalen-2-ylmethoxy)piperidine |
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| Synonym | More Synonyms |
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Litoxetine BiologicalActivity
| Description | Litoxetine (SL 81.0385) is a selective 5-HT uptake inhibitor. Litoxetine is a 5-HT3 receptor antagonist with a Ki of 85 nM for cerebral 5-HT3 receptors. Litoxetine is an antidepressant and has antiemetic properties[1]. |
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| Related Catalog | Research Areas >>Neurological DiseaseSignaling Pathways >>GPCR/G Protein >>5-HT ReceptorSignaling Pathways >>Neuronal Signaling >>5-HT Receptor |
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| References | [1]. I Angel, et al. Litoxetine: a selective 5-HT uptake inhibitor with concomitant 5-HT3 receptor antagonist and antiemetic properties. Eur J Pharmacol. 1993 Mar 2;232(2-3):139-45. |
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Chemical & Physical Properties
| Density | 1.1g/cm3 |
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| Boiling Point | 387.1ºC at 760 mmHg |
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| Molecular Formula | C16H19NO |
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| Molecular Weight | 241.32800 |
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| Flash Point | 159.2ºC |
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| Exact Mass | 241.14700 |
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| PSA | 21.26000 |
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| LogP | 3.43720 |
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| Index of Refraction | 1.607 |
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| InChIKey | MJJDYOLPMGIWND-UHFFFAOYSA-N |
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| SMILES | c1ccc2cc(COC3CCNCC3)ccc2c1 |
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Synonyms
| Litoxetinum [INN-Latin] |
| Litoxetina |
| Litoxetine |
| Litoxetinum |
| Litoxetina [INN-Spanish] |
