Introduction：Basic information about CAS 115416-38-1|5-(Biotinamido)pentylamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5-(Biotinamido)pentylamine |
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| CAS Number | 115416-38-1 | Molecular Weight | 328.47300 |
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| Density | 1.131g/cm3 | Boiling Point | 652ºC at 760mmHg |
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| Molecular Formula | C15H28N4O2S | Melting Point | / |
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| MSDS | / | Flash Point | 348.1ºC |
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Names
| Name | 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-(5-aminopentyl)pentanamide |
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| Synonym | More Synonyms |
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5-(Biotinamido)pentylamine BiologicalActivity
| Description | 5-Biotinamidopentylamine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | Alkyl-Chain |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.131g/cm3 |
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| Boiling Point | 652ºC at 760mmHg |
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| Molecular Formula | C15H28N4O2S |
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| Molecular Weight | 328.47300 |
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| Flash Point | 348.1ºC |
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| Exact Mass | 328.19300 |
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| PSA | 128.53000 |
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| LogP | 2.46680 |
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| Vapour Pressure | 7.01E-17mmHg at 25°C |
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| Index of Refraction | 1.529 |
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| InChIKey | CCSGGWGTGOLEHK-OBJOEFQTSA-N |
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| SMILES | NCCCCCNC(=O)CCCCC1SCC2NC(=O)NC21 |
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| Storage condition | -20°C |
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Synonyms
| Biotinyl cadaverine |
| Cadaverine-X-biotin |
| Biotincadaverine |
