CAS 192-65-4|dibenzo[a,e]pyrene

Introduction：Basic information about CAS 192-65-4|dibenzo[a,e]pyrene, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
4. Safety Information
5. Customs
6. Articles4
7. Synonyms

Common Name	dibenzo[a,e]pyrene
CAS Number	192-65-4	Molecular Weight	302.368
Density	1.3±0.1 g/cm3	Boiling Point	552.3±17.0 °C at 760 mmHg
Molecular Formula	C₂₄H₁₄	Melting Point	233.5ºC
MSDS	USA	Flash Point	282.0±15.1 °C
Symbol	GHS05, GHS08	Signal Word	Danger

Names

Name	Dibenzo(a,e)pyrene
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	552.3±17.0 °C at 760 mmHg
Melting Point	233.5ºC
Molecular Formula	C₂₄H₁₄
Molecular Weight	302.368
Flash Point	282.0±15.1 °C
Exact Mass	302.109558
LogP	7.63
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.913
InChIKey	KGHMWBNEMFNJFZ-UHFFFAOYSA-N
SMILES	c1ccc2c(c1)cc1c3ccccc3c3cccc4ccc2c1c43
Storage condition	2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QL0175000

CHEMICAL NAME :: Naphtho(1,2,3,4-def)chrysene

CAS REGISTRY NUMBER :: 192-65-4

BEILSTEIN REFERENCE NO. :: 2054070

LAST UPDATED :: 199710

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C24-H14

MOLECULAR WEIGHT :: 302.38

WISWESSER LINE NOTATION :: L D66 L666 B6 2AB A&J

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 312 mg/kg/52W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 72 mg/kg/9W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 25 nmol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 342,9,1995 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 3,201,1973 IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,327,1983 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,327,1983 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FRANCE;Carcinogen JAN 1993

Safety Information

Symbol	GHS05, GHS08
Signal Word	Danger
Hazard Statements	H341-H350
Precautionary Statements	P201-P202-P281-P308 + P313-P405-P501
Hazard Codes	Xn
Risk Phrases	40-41
Safety Phrases	26-39
RIDADR	UN 2811
RTECS	QL0175000
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2902909090

Customs

HS Code	2902909090
Summary	2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

Articles4

Polycyclic aromatic hydrocarbons: 15 Listings - benz[a]anthracene, benzo[b]fluoranthene, benzo[j]fluoranthene, benzo[k]fluoranthene, benzo[a]pyrene, dibenz[a,h]acridine, dibenz[a,j]acridine, dibenz[a,h]anthracene, 7H-dibenzo[c,g]carbazole, dibenzo[a,e]pyrene, dibenzo[a,h]pyrene, dibenzo[a,i]pyrene, dibenzo[a,l]pyrene, indeno[1,2,3-cd]pyrene, 5-methylchrysene.

Rep. Carcinog. 12 , 353-61, (2011)

Determination of 23 polycyclic aromatic hydrocarbons in atmospheric particulate matter of the Paris area and photolysis by sunlight.

Int. J. Environ. Anal. Chem. 19(2) , 111-31, (1985)

Twenty-three polycyclic aromatic hydrocarbons (PAH) were determined in atmospheric particulate matter in 4 places of the Paris area at several times of the year. Fractionation was performed by reverse...

Dibenzo[a,e]pyrene.

IARC Monogr. Eval. Carcinog. Risk Chem. Hum. 32 , 327-30, (1983)

Synonyms

Dibenzo[f,pqr]tetraphene

dibenzo(a,e)pyrene

dibenzo[a,e]pyrene

Naphtho[1,2,3,4-def]chrysene

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