Introduction：Basic information about CAS 35369-53-0|HBED dihydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | HBED dihydrochloride |
|---|
| CAS Number | 35369-53-0 | Molecular Weight | 461.34 |
|---|
| Density | / | Boiling Point | / |
|---|
| Molecular Formula | C20H26Cl2N2O6 | Melting Point | 130-134ºC |
|---|
| MSDS | / | Flash Point | / |
|---|
Names
| Name | hbed hcl h2o |
|---|
| Synonym | More Synonyms |
|---|
HBED dihydrochloride BiologicalActivity
| Description | HBED dihydrochloride is an orally active and hexadentate phenolic aminocarboxylate iron chelator. HBED refers to N, N'-bis(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid, inducing iron excretion in primates. HBED dihydrochloride has the potential to be used as an alternative to desferriamine for iron chelation therapy[1]. |
|---|
| Related Catalog | Research Areas >>Others |
|---|
| In Vivo | HBED monohydrochloride dihydrate 在不同的给药方式下，产生的活性不同。HBED 以 81、162 和 324 μMol/kg 的剂量，口服给药后不会产生显著效果。而以 162 和 324 μMol/kg 的剂量，在皮下给药后，提高了净铁排泄量[1]。 |
|---|
| References | [1]. Bergeron RJ, et al. HBED: the continuing development of a potential alternative to deferoxamine for iron-chelating therapy. Blood. 1999 Jan 1;93(1):370-5. |
|---|
Chemical & Physical Properties
| Melting Point | 130-134ºC |
|---|
| Molecular Formula | C20H26Cl2N2O6 |
|---|
| Molecular Weight | 461.34 |
|---|
| Exact Mass | 388.16300 |
|---|
| PSA | 121.54000 |
|---|
| LogP | 1.57120 |
|---|
| InChIKey | LLSTUPXEHRIYKM-UHFFFAOYSA-N |
|---|
| SMILES | Cl.O.O=C(O)CN(CCN(CC(=O)O)Cc1ccccc1O)Cc1ccccc1O |
|---|
Safety Information
| Risk Phrases | 36/37/38 |
|---|
| Safety Phrases | 26-36/37/39 |
|---|
Synonyms
