Introduction:Basic information about CAS 872679-70-4|Fmoc-NH-PEG2-CH2CH2COOH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Fmoc-NH-PEG2-CH2CH2COOH |
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| CAS Number | 872679-70-4 | Molecular Weight | 399.437 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 622.1±55.0 °C at 760 mmHg |
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| Molecular Formula | C22H25NO6 | Melting Point | / |
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| MSDS | / | Flash Point | 330.0±31.5 °C |
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Names
| Name | Fmoc-9-Amino-4,7-dioxanonanoic acid |
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| Synonym | More Synonyms |
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Fmoc-NH-PEG2-CH2CH2COOH BiologicalActivity
| Description | Fmoc-NH-PEG2-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC Linker |
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| Target | Cleavable |
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| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
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| References | [1]. Fulcher JM, et al. Chemical synthesis of Shiga toxin subunit B using a next-generation traceless "helping hand" solubilizing tag. Org Biomol Chem. 2019 Dec 28;17(48):10237-10244. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 622.1±55.0 °C at 760 mmHg |
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| Molecular Formula | C22H25NO6 |
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| Molecular Weight | 399.437 |
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| Flash Point | 330.0±31.5 °C |
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| Exact Mass | 399.168182 |
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| PSA | 97.58000 |
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| LogP | 2.96 |
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| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
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| Index of Refraction | 1.584 |
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| InChIKey | QWHLFJJLRVOHTM-UHFFFAOYSA-N |
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| SMILES | O=C(O)CCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc21 |
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| Storage condition | -20 ℃ |
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Safety Information
| Hazard Codes | Xi |
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| HS Code | 2932999099 |
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Customs
| HS Code | 2932999099 |
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| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 3-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]propanoic acid |
| 2,7,10-Trioxa-4-azatridecan-13-oic acid, 1-(9H-fluoren-9-yl)-3-oxo- |
| 3-{2-[2-Amino-3-(9H-fluoren-9-ylmethoxy)-3-oxopropoxy]ethoxy}propanoic acid |
| Serine, O-[2-(2-carboxyethoxy)ethyl]-, 9H-fluoren-9-ylmethyl ester |
| 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10-trioxa-4-azatridecan-13-oic acid |
| Fmoc-NH-PEG2-CH2CH2COOH |