CAS 872679-70-4|Fmoc-NH-PEG2-CH2CH2COOH

Introduction:Basic information about CAS 872679-70-4|Fmoc-NH-PEG2-CH2CH2COOH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameFmoc-NH-PEG2-CH2CH2COOH
CAS Number872679-70-4Molecular Weight399.437
Density1.3±0.1 g/cm3Boiling Point622.1±55.0 °C at 760 mmHg
Molecular FormulaC22H25NO6Melting Point/
MSDS/Flash Point330.0±31.5 °C

Names

NameFmoc-9-Amino-4,7-dioxanonanoic acid
SynonymMore Synonyms

Fmoc-NH-PEG2-CH2CH2COOH BiologicalActivity

DescriptionFmoc-NH-PEG2-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC Linker
Target

Cleavable

In VitroADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Fulcher JM, et al. Chemical synthesis of Shiga toxin subunit B using a next-generation traceless "helping hand" solubilizing tag. Org Biomol Chem. 2019 Dec 28;17(48):10237-10244.

Chemical & Physical Properties

Density1.3±0.1 g/cm3
Boiling Point622.1±55.0 °C at 760 mmHg
Molecular FormulaC22H25NO6
Molecular Weight399.437
Flash Point330.0±31.5 °C
Exact Mass399.168182
PSA97.58000
LogP2.96
Vapour Pressure0.0±1.9 mmHg at 25°C
Index of Refraction1.584
InChIKeyQWHLFJJLRVOHTM-UHFFFAOYSA-N
SMILESO=C(O)CCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc21
Storage condition-20 ℃

Safety Information

Hazard CodesXi
HS Code2932999099

Customs

HS Code2932999099
Summary2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

3-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]propanoic acid
2,7,10-Trioxa-4-azatridecan-13-oic acid, 1-(9H-fluoren-9-yl)-3-oxo-
3-{2-[2-Amino-3-(9H-fluoren-9-ylmethoxy)-3-oxopropoxy]ethoxy}propanoic acid
Serine, O-[2-(2-carboxyethoxy)ethyl]-, 9H-fluoren-9-ylmethyl ester
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10-trioxa-4-azatridecan-13-oic acid
Fmoc-NH-PEG2-CH2CH2COOH
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