Introduction：Basic information about CAS 911004-72-3|Furowanin A, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Furowanin A |
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| CAS Number | 911004-72-3 | Molecular Weight | 438.47 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 697.7±55.0 °C at 760 mmHg |
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| Molecular Formula | C25H26O7 | Melting Point | / |
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| MSDS | / | Flash Point | 240.3±25.0 °C |
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Names
| Name | Furowanin A |
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| Synonym | More Synonyms |
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Furowanin A BiologicalActivity
| Description | Furowanin A is a flavonoid with anti-neoplastic effects. Furowanin A inhibits STAT3/Mcl-1 axis to suppress proliferation, block cell cycle progression, induce apoptosis and promote autophagy. Furowanin A potently inhibits colorectal cancer (CRC) cells[1]. |
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| Related Catalog | Signaling Pathways >>Apoptosis >>Bcl-2 FamilySignaling Pathways >>Stem Cell/Wnt >>STATResearch Areas >>CancerSignaling Pathways >>JAK/STAT Signaling >>STAT |
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| Target | Mcl-1 STAT3 |
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| References | [1]. Ma Z, et al. Furowanin A-induced autophagy alleviates apoptosis and promotes cell cycle arrest via inactivation STAT3/Mcl-1 axis in colorectal cancer. Life Sci. 2019 Feb 1;218:47-57. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 697.7±55.0 °C at 760 mmHg |
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| Molecular Formula | C25H26O7 |
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| Molecular Weight | 438.47 |
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| Flash Point | 240.3±25.0 °C |
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| Exact Mass | 438.167847 |
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| PSA | 120.36000 |
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| LogP | 5.34 |
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| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
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| Index of Refraction | 1.661 |
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| InChIKey | NMEQUFXTRAXRGN-UHFFFAOYSA-N |
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| SMILES | CC(C)=CCc1c2c(c(O)c3c(=O)c(-c4ccc(O)c(O)c4)coc13)CC(C(C)(C)O)O2 |
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Safety Information
Synonyms
| 6-(3,4-Dihydroxyphenyl)-4-hydroxy-2-(2-hydroxy-2-propanyl)-9-(3-methyl-2-buten-1-yl)-2,3-dihydro-5H-furo[3,2-g]chromen-5-one |
| 5H-Furo[3,2-g][1]benzopyran-5-one, 6-(3,4-dihydroxyphenyl)-2,3-dihydro-4-hydroxy-2-(1-hydroxy-1-methylethyl)-9-(3-methyl-2-buten-1-yl)- |
