Introduction：Basic information about CAS 404830-45-1|15-Keto Travoprost, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 15-Keto Travoprost |
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| CAS Number | 404830-45-1 | Molecular Weight | 498.532 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 577.5±50.0 °C at 760 mmHg |
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| Molecular Formula | C26H33F3O6 | Melting Point | / |
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| MSDS | / | Flash Point | 303.1±30.1 °C |
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Names
| Name | propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoate |
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| Synonym | More Synonyms |
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15-Keto Travoprost BiologicalActivity
| Description | 15-Keto Travoprost (15-Keto Fluprostenol isopropyl ester) is a metabolite of Travoprost (HY-B0584). 15-Keto Travoprost shows stimulatory effect on the growth and thickening of the eyelashes[1][2]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| In Vitro | 15-Keto Travoprost (80 µgr/mL) can be used for the treatment of idiopathic hypotrichosis of the eyelashes[1]. |
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| References | [1]. Fabbrocini G, et al. 15 keto fluprostenol isopropyl ester (80 µgr/mL) gel for cosmetic eyelash growth and enhancement. J Cosmet Dermatol. 2019 Apr;18(2):545-549. [2]. Ciro C, et al. Effect of Fluprostenol Isopropyl Ester and 15-Keto Fluprostenol on Eyelash Growth: A Clinical and Pharmacologic Study. Skinmed. 2018 Jul 1;16(4):231-233. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 577.5±50.0 °C at 760 mmHg |
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| Molecular Formula | C26H33F3O6 |
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| Molecular Weight | 498.532 |
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| Flash Point | 303.1±30.1 °C |
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| Exact Mass | 498.222931 |
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| PSA | 93.06000 |
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| LogP | 3.82 |
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| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
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| Index of Refraction | 1.541 |
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| InChIKey | KSDDYCRRTVADFZ-OHDKTVHDSA-N |
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| SMILES | CC(C)OC(=O)CCCC=CCC1C(O)CC(O)C1C=CC(=O)COc1cccc(C(F)(F)F)c1 |
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Synonyms
| 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-, 1-methylethyl ester, (5Z)- |
| Travoprost impurity,15-keto derivative-[USP] |
| UNII-4U2P9U9Z66 |
| Isopropyl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl}cyclopentyl]-5-heptenoate |
| 15-Oxo travoprost |
| 15-keto Fluprostenol isopropyl ester |
| 15-Keto Travoprost |
| (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester |
| (5Z,13E)-(9S,11R)-9,11,-Dihydroxy-15-oxo-16-(m-trifluoromethylphenoxy)-17,18,19,20-tetranor-5,13-prostadienoic acid,isopropyl ester |
