Introduction：Basic information about CAS 57653-85-7|1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin |
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| CAS Number | 57653-85-7 | Molecular Weight | 390.86100 |
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| Density | 1.777 g/cm3 | Boiling Point | 478ºC at 760 mmHg |
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| Molecular Formula | C12H2Cl6O2 | Melting Point | 285-286ºC |
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| MSDS | / | Flash Point | 182.9ºC |
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Names
| Name | 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.777 g/cm3 |
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| Boiling Point | 478ºC at 760 mmHg |
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| Melting Point | 285-286ºC |
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| Molecular Formula | C12H2Cl6O2 |
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| Molecular Weight | 390.86100 |
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| Flash Point | 182.9ºC |
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| Exact Mass | 387.81900 |
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| PSA | 18.46000 |
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| LogP | 7.50500 |
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| InChIKey | YCLUIPQDHHPDJJ-UHFFFAOYSA-N |
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| SMILES | Clc1cc2c(c(Cl)c1Cl)Oc1cc(Cl)c(Cl)c(Cl)c1O2 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- HP3280100
- CHEMICAL NAME :
- Dibenzo-p-dioxin, 1,2,3,6,7,8-hexachloro-
- CAS REGISTRY NUMBER :
- 57653-85-7
- BEILSTEIN REFERENCE NO. :
- 1627652
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C12-H2-Cl6-O2
- MOLECULAR WEIGHT :
- 390.84
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1250 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 70 ug/kg
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 140 ug/kg/14D-C
- TOXIC EFFECTS :
- Immunological Including Allergic - decrease in humoral immune response
MUTATION DATA - TYPE OF TEST :
- Morphological transformation
- TEST SYSTEM :
- Rodent - mouse Fibroblast
- DOSE/DURATION :
- 400 pmol/L
- REFERENCE :
- CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 8,1485,1987 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 69,33,1997
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Safety Information
| RIDADR | UN 2811 |
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| Packaging Group | I |
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| Hazard Class | 6.1(a) |
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Synonyms
| 1,2,3,6,7,8-hexachlorodibenzo-p-dioxin |
