CAS 541-59-3|Maleimide

Introduction:Basic information about CAS 541-59-3|Maleimide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameMaleimide
CAS Number541-59-3Molecular Weight97.072
Density1.4±0.1 g/cm3Boiling Point264.4±23.0 °C at 760 mmHg
Molecular FormulaC4H3NO2Melting Point91-93 °C(lit.)
MSDSChineseUSAFlash Point113.7±22.6 °C
Symbol
GHS05, GHS06
Signal WordDanger

Names

Namemaleimide
SynonymMore Synonyms

Chemical & Physical Properties

Density1.4±0.1 g/cm3
Boiling Point264.4±23.0 °C at 760 mmHg
Melting Point91-93 °C(lit.)
Molecular FormulaC4H3NO2
Molecular Weight97.072
Flash Point113.7±22.6 °C
Exact Mass97.016380
PSA46.17000
LogP-0.69
Vapour Pressure0.0±1.2 mmHg at 25°C
Index of Refraction1.606
InChIKeyPEEHTFAAVSWFBL-UHFFFAOYSA-N
SMILESO=C1C=CC(=O)N1
Storage conditionRefrigerator
Water SolubilitySOLUBLE

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ON4800000
CHEMICAL NAME :
Maleimide
CAS REGISTRY NUMBER :
541-59-3
BEILSTEIN REFERENCE NO. :
0106910
LAST UPDATED :
199710
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C4-H3-N-O2
MOLECULAR WEIGHT :
97.08
WISWESSER LINE NOTATION :
T5VMVJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
80 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 40(11),109,1975
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
7766 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 37,15,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
9 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - hemorrhage Behavioral - convulsions or effect on seizure threshold Nutritional and Gross Metabolic - other changes
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 27,151,1978 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
750 ug/kg
SEX/DURATION :
female 9 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 37,15,1976
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
3100 ug/kg
SEX/DURATION :
female 9 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 37,15,1976

Safety Information

Symbol
GHS05, GHS06
Signal WordDanger
Hazard StatementsH301-H314-H317
Precautionary StatementsP280-P301 + P310-P305 + P351 + P338-P310
Personal Protective EquipmentEyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard CodesT:Toxic;
Risk PhrasesR25;R36/37/38;R43
Safety PhrasesS26-S36/37/39-S45-S37/39-S28A
RIDADRUN 2923 8/PG 2
WGK Germany3
RTECSON4800000
Packaging GroupIII
Hazard Class8
HS Code29251995

Customs

HS Code2925190090
Summary2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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Synonyms

maleic acid imide
monomaleimide
Maleic imide
EINECS 208-787-4
1H-Pyrrole-2.5-dione
3-pyrroline-2,5-dione
Maleimide
Maleinimide
pyrroline-2,5-dion
2,5-Pyrroledione
1H-Pyrrole-2,5-dione
N-hydroxysuccinimide
MFCD00005494
Pyrrole-2,5-dione
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