Introduction：Basic information about CAS 121822-32-0|AC-SER-GLN-ASN-TYR-PRO-VAL-VAL-NH2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | AC-SER-GLN-ASN-TYR-PRO-VAL-VAL-NH2 |
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| CAS Number | 121822-32-0 | Molecular Weight | 846.92700 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C38H58N10O12 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 2-[(2-acetamido-3-hydroxypropanoyl)amino]-N-[4-amino-1-[[1-[2-[[1-[(1-amino-3-methyl-1-oxobutan-2-yl)amino]-3-methyl-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]pentanediamide |
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| Synonym | More Synonyms |
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AC-SER-GLN-ASN-TYR-PRO-VAL-VAL-NH2 BiologicalActivity
| Description | Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2 is a substrato peptídico of HIV-1 protease.Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2 acts as the variable substrate in a peptidolytic assay to quantify the inhibition of the protease[1][2]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Metabolic Enzyme/Protease >>HIV Protease |
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| References | [1]. Ana C. R. Sodero, et al. Mecanismo Catalítico e Estado de Protonação do Sítio Ativo de Aspartil Proteases Pepsina-Símiles.Revista Virtual de Química, v. 1 n. 2 (2009). [2]. G B Dreyer, et al. Inhibition of human immunodeficiency virus 1 protease in vitro: rational design of substrate analogue inhibitors. Proc Natl Acad Sci U S A. 1989 Dec;86(24):9752-6. |
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Chemical & Physical Properties
| Molecular Formula | C38H58N10O12 |
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| Molecular Weight | 846.92700 |
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| Exact Mass | 846.42400 |
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| PSA | 364.64000 |
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| LogP | 0.16910 |
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| InChIKey | XYZIULLGTDZPIP-UHFFFAOYSA-N |
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| SMILES | CC(=O)NC(CO)C(=O)NC(CCC(N)=O)C(=O)NC(CC(N)=O)C(=O)NC(Cc1ccc(O)cc1)C(=O)N1CCCC1C(=O)NC(C(=O)NC(C(N)=O)C(C)C)C(C)C |
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Synonyms
| Acetyl-Ser-Gln-Asn-Tyr-Pro-Val-Val amide |
