Introduction：Basic information about CAS 7327-87-9|Dihydralazine sulfate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Dihydralazine sulfate |
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| CAS Number | 7327-87-9 | Molecular Weight | 288.284 |
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| Density | / | Boiling Point | 648.3ºC |
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| Molecular Formula | C8H12N6O4S | Melting Point | / |
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| MSDS | / | Flash Point | 345.9ºC |
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Names
| Name | (4-hydrazinylphthalazin-1-yl)hydrazine,sulfuric acid |
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| Synonym | More Synonyms |
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Dihydralazine sulfate BiologicalActivity
| Description | Dihydralazine sulfate is an antihypertensive agent. |
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| Related Catalog | Signaling Pathways >>Others >>Others |
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| References | [1]. Bijvank SW, et al. Ketanserin versus dihydralazine for the treatment of severe hypertension in early-onset preeclampsia: a double blind randomized controlled trial. Eur J Obstet Gynecol Reprod Biol. 2015 Jun;189:106-11. |
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Chemical & Physical Properties
| Boiling Point | 648.3ºC |
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| Molecular Formula | C8H12N6O4S |
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| Molecular Weight | 288.284 |
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| Flash Point | 345.9ºC |
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| Exact Mass | 288.064087 |
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| PSA | 184.86000 |
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| LogP | 2.17560 |
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| InChIKey | BWHAMWGGORIDBK-UHFFFAOYSA-N |
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| SMILES | NNc1nnc(NN)c2ccccc12.O=S(=O)(O)O |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- TH8880000
- CAS REGISTRY NUMBER :
- 7327-87-9
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C8-H10-N6.H2-O4-S
- MOLECULAR WEIGHT :
- 288.32
- WISWESSER LINE NOTATION :
- T66 CNNJ BMZ EMZ &S-O4
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 159 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 223 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- DNA damage
MUTATION DATA - TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 79500 ug/kg
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 4,605,1982
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Safety Information
| RIDADR | NONH for all modes of transport |
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Synonyms
| EINECS 230-808-0 |
| Depressan |
| 1,4-dihydrazino-phthalazine,sulfate |
| MFCD00035271 |
| dihydrazino-1,4-phthalazine sulfate |
| 1,4-dihydrazinophthalazine sulfate(1:1) |
| Phthalazine,1,4-dihydrazino-,sulfate (1:1) |
| Phthalazine, 1,4-bis(hydrazinyl)-, sulfate (1:1) |
| 1,4-Dihydrazino-phthalazin,Sulfat |
| 1,4-dihydrazinylphthalazine sulfate (1:1) |
| 1,4-Dihydrazinophthalazine hydrogen sulfate |
| (1Z,4Z)-1,4-dihydrazinylidene-1,2,3,4-tetrahydrophthalazine sulfate (1:1) |
| Dihydralazine sulphate |
| Sulfate de dihydralazine [French] |
| 4-Hydrazino-1-hydrazono-1,2-dihydrophthalazine sulfate (1:1) |
| Dihydralazine sulfate |
| 1,4-phthalazinedione, 2,3-dihydro-, dihydrazone, (1Z,4Z)-, sulfate (1:1) |
| dihydralazine |
