CAS 142-63-2|Piperazine Hexahydrate
Introduction：Basic information about CAS 142-63-2|Piperazine Hexahydrate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Piperazine Hexahydrate | ||
|---|---|---|---|
| CAS Number | 142-63-2 | Molecular Weight | 194.22700 |
| Density | 1.92g/cm3 | Boiling Point | 145-156 °C(lit.) |
| Molecular Formula | C4H22N2O6 | Melting Point | 42-44 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 190 °F |
| Symbol | GHS05, GHS08 | Signal Word | Danger |
Names
| Name | Piperazine Hexahydrate |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.92g/cm3 |
|---|---|
| Boiling Point | 145-156 °C(lit.) |
| Melting Point | 42-44 °C(lit.) |
| Molecular Formula | C4H22N2O6 |
| Molecular Weight | 194.22700 |
| Flash Point | 190 °F |
| Exact Mass | 194.14800 |
| PSA | 79.44000 |
| Vapour Pressure | 4.05mmHg at 25°C |
| InChIKey | AVRVZRUEXIEGMP-UHFFFAOYSA-N |
| SMILES | C1CNCCN1.O.O.O.O.O.O |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 90,260,1947
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 11200 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia Gastrointestinal - hypermotility, diarrhea
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 6,336,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84706 No. of Facilities: 68 (estimated) No. of Industries: 1 No. of Occupations: 6 No. of Employees: 2770 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84706 No. of Facilities: 9 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 127 (estimated) No. of Female Employees: 45 (estimated)
Safety Information
| Symbol | GHS05, GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H314-H317-H334-H361fd |
| Precautionary Statements | P260-P280-P284-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338 |
| Hazard Codes | C:Corrosive; |
| Risk Phrases | R34;R42/43;R52/53 |
| Safety Phrases | S22-S26-S36/37/39-S45-S61 |
| RIDADR | UN 2579 8/PG 3 |
| WGK Germany | 1 |
| RTECS | TM0850000 |
| Packaging Group | III |
| Hazard Class | 8 |
| HS Code | 2933599090 |
Customs
| HS Code | 2933599090 |
|---|---|
| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles28
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| Synthesis and anti-inflammatory effects of new piperazine and ethanolamine derivatives of H(1)-antihistaminic drugs. Mini Rev. Med. Chem. 12(12) , 1282-92, (2012) In addition to their antihistamine effects, H1-receptor antagonists possess pharmacological properties that are not uniformly distributed among this class of drugs, such as anti-inflammatory, anti-all... | |
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Synonyms
| Diethylenediamine Hexahydrate |
| piperazine,hexahydrate |
| Piperazine hydrate |
| Piperazine hexahydrate |
| EINECS 203-808-3 |
| MFCD00149389 |
