CAS 14259-45-1|Asperuloside
| Common Name | Asperuloside | ||
|---|---|---|---|
| CAS Number | 14259-45-1 | Molecular Weight | 414.361 |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 704.2±60.0 °C at 760 mmHg |
| Molecular Formula | C18H22O11 | Melting Point | 131-132° |
| MSDS | ChineseUSA | Flash Point | 254.1±26.4 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | asperuloside |
|---|---|
| Synonym | More Synonyms |
Asperuloside BiologicalActivity
| Description | Asperuloside is an iridoid isolated from Hedyotis diffusa, with anti-inflammatory activity. Asperuloside inhibits inducible nitric oxide synthase (iNOS), suppresses NF-κB and MAPK signaling pathways[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Immunology/Inflammation >>NO SynthaseResearch Areas >>Inflammation/Immunology |
| References | [1]. He J, et al. Asperuloside and Asperulosidic Acid Exert an Anti-Inflammatory Effect via Suppression of the NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages. Int J Mol Sci. 2018 Jul 12;19(7). |
Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 704.2±60.0 °C at 760 mmHg |
| Melting Point | 131-132° |
| Molecular Formula | C18H22O11 |
| Molecular Weight | 414.361 |
| Flash Point | 254.1±26.4 °C |
| Exact Mass | 414.116211 |
| PSA | 161.21000 |
| LogP | -3.28 |
| Vapour Pressure | 0.0±5.1 mmHg at 25°C |
| Index of Refraction | 1.635 |
| InChIKey | IBIPGYWNOBGEMH-DILZHRMZSA-N |
| SMILES | CC(=O)OCC1=CC2OC(=O)C3=COC(OC4OC(CO)C(O)C(O)C4O)C1C32 |
| Storage condition | 2-8C |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Hazard Codes | Xn |
| Risk Phrases | 22 |
| RIDADR | NONH for all modes of transport |
Articles11
More Articles| Chemical constituents of the fruits of Morinda citrifolia (Noni) and their antioxidant activity. J. Nat. Prod. 68 , 592-5, (2005) Purification of a n-BuOH-soluble partition of the MeOH extract of Morinda citrifolia (Noni) fruits led to the isolation of two new iridoid glucosides, 6alpha-hydroxyadoxoside (1) and 6beta,7beta-epoxy... | |
| [Chemical constituents from root of Lasianthus acuminatissimus I]. Zhongguo Zhong Yao Za Zhi 31(2) , 133-5, (2006) To investigate the chemical constituents from the root of Lasianthus acuminatissimus of Rubiaceae.Normal, reverse phase silica gel, macroporous resin column and HPLC chromatography were used for isola... | |
| [Isolation and identification of chemical constituents from Hedyotis chrysotricha (Palib.) Merr]. Zhongguo Zhong Yao Za Zhi 17(2) , 98-100, 127, (1992) |
Synonyms
| [5-(Hexopyranosyloxy)-1-oxo-2a,4a,5,7b-tetrahydro-1H-2,6-dioxacyclopenta[cd]inden-4-yl]methyl acetate |
| Asperulosid |
| RUBICHLORIC ACID |
| ASPERULOSIDE |
| 1H-2,6-Dioxacyclopent[cd]inden-1-one, 4-[(acetyloxy)methyl]-5-(hexopyranosyloxy)-2a,4a,5,7b-tetrahydro- |
