CAS 38260-01-4|TRIETHYLENETETRAMINE DIHYDROCHLORIDE

CHEMICAL IDENTIFICATION

RTECS NUMBER :

KH8587085

CHEMICAL NAME :

1,2-Ethanediamine, N,N'-bis(2-aminoethyl)-, dihydrochloride

CAS REGISTRY NUMBER :

38260-01-4

LAST UPDATED :

199612

DATA ITEMS CITED :

4

MOLECULAR FORMULA :

C6-H18-N4.2Cl-H

MOLECULAR WEIGHT :

219.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

2285 mg/kg

TOXIC EFFECTS :

Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - other changes Gastrointestinal - ulceration or bleeding from stomach

REFERENCE :

TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: (Suppl),246,1992 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

67500 mg/kg/90D-I

TOXIC EFFECTS :

Lungs, Thorax, or Respiration - other changes Liver - fatty liver degeneration Blood - changes in spleen

REFERENCE :

FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 29,185,1996 ** REPRODUCTIVE DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

1140 uL/kg

SEX/DURATION :

female 1-19 day(s) after conception

TOXIC EFFECTS :

Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - other effects to embryo

REFERENCE :

JNSVA5 Journal of Nutritional Science and Vitaminology. (Business Center for Academic Soc. Japan, 2-4-16 Yayoi, Bunkyo-ku, Tokyo 113, Japan) V.19- 1973- Volume(issue)/page/year: 38,545,1992

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

22800 mg/kg

SEX/DURATION :

female 1-19 day(s) after conception

TOXIC EFFECTS :

Reproductive - Specific Developmental Abnormalities - Central Nervous System

REFERENCE :

JNSVA5 Journal of Nutritional Science and Vitaminology. (Business Center for Academic Soc. Japan, 2-4-16 Yayoi, Bunkyo-ku, Tokyo 113, Japan) V.19- 1973- Volume(issue)/page/year: 39,177,1993

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