CAS 20357-25-9|6-Nitroveratraldehyde

Introduction：Basic information about CAS 20357-25-9|6-Nitroveratraldehyde, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 6-Nitroveratraldehyde BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Articles2
7. Synonyms

Common Name	6-Nitroveratraldehyde
CAS Number	20357-25-9	Molecular Weight	211.17100
Density	1.312 g/cm3	Boiling Point	390.8ºC at 760 mmHg
Molecular Formula	C₉H₉NO₅	Melting Point	133.2-134.5 °C
MSDS	USA	Flash Point	194.3ºC

Names

Name	4,5-dimethoxy-2-nitrobenzaldehyde
Synonym	More Synonyms

6-Nitroveratraldehyde BiologicalActivity

Description	DMNB (6-Nitroveratraldehyde), a precursor, can be used for the synthesis no-carrier-added 6-[18F]fluoro-L-DOPA (6-FDOPA). No-Carrier-Added (NCA) 6-[18F]fluoro-L-dopa (6-FDOPA) is being produced routinely for PET investigations of dopaminergic systems[1].
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease
References	[1]. Zhang Lan, et al. Preparation of 6-[¹⁸F]fluoro-L-DOPA and its biodistribution in normal and unilateral PD model rats. Nuclear Science and Techniques, 13(4), 244-250. [2]. Reddy GN, et al. Quality assurance and quality control methods for animal and human applications of no-carrier-added 6-[18F]fluorodopa for PET investigations of dopaminergic systems. Appl Radiat Isot. 1993;44(7):993-998.

Description

DMNB (6-Nitroveratraldehyde), a precursor, can be used for the synthesis no-carrier-added 6-[18F]fluoro-L-DOPA (6-FDOPA). No-Carrier-Added (NCA) 6-[18F]fluoro-L-dopa (6-FDOPA) is being produced routinely for PET investigations of dopaminergic systems[1].

Related Catalog

Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease

References

[1]. Zhang Lan, et al. Preparation of 6-[¹⁸F]fluoro-L-DOPA and its biodistribution in normal and unilateral PD model rats. Nuclear Science and Techniques, 13(4), 244-250.

[2]. Reddy GN, et al. Quality assurance and quality control methods for animal and human applications of no-carrier-added 6-[18F]fluorodopa for PET investigations of dopaminergic systems. Appl Radiat Isot. 1993;44(7):993-998.

Chemical & Physical Properties

Density	1.312 g/cm3
Boiling Point	390.8ºC at 760 mmHg
Melting Point	133.2-134.5 °C
Molecular Formula	C₉H₉NO₅
Molecular Weight	211.17100
Flash Point	194.3ºC
Exact Mass	211.04800
PSA	81.35000
LogP	1.94770
Vapour Pressure	2.59E-06mmHg at 25°C
Index of Refraction	1.571
InChIKey	YWSPWKXREVSQCA-UHFFFAOYSA-N
SMILES	COc1cc(C=O)c([N+](=O)[O-])cc1OC
Storage condition	2-8°C
Water Solubility	DMSO: 22 mg/mL

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi: Irritant;
Safety Phrases	S24/25
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	GY8410000
HS Code	2913000090

Customs

HS Code	2913000090
Summary	HS: 2913000090 halogenated, sulphonated, nitrated or nitrosated derivatives of products of heading 2912 Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:none Most favored nation tariff:5.5% General tariff:30.0%

Articles2

An improved synthesis of no-carrier-added (NCA) 6-[¹⁸ F] Fluoro-l-DOPA and its remote routine production for PET investigations of dopaminergic systems. Reddy GN, et al.

Appl. Radiat. Isot. 44(4) , 645-49, (1993)

o-Nitroaryl-bis (5-methylfur-2-yl) methanes as Versatile Synthons for the Synthesis of Nitrogen-Containing Heterocycles. Butin AV, et al.

Molecules 2(4) , 62-8, (1997)

Synonyms

4,5-dimethoxy-2-nitro-benzaldehyde

Benzaldehyde,4,5-dimethoxy-2-nitro

3,4-Dimethoxy-6-nitrobenzaldehyde

6-Nitroveratraldehyde

2-nitro-4,5-dimethoxybenzaldehyde

DNA-Dependent Protein Kinase Inhibitor

DMNB

EINECS 243-762-1

MFCD00007134

DNA-PK Inhibitor

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